Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12748229 | 0.90 | TSPO (0.44) | TSPO | |
| SCHEMBL12748236 | 0.90 | TSPO (0.44) | TSPO | |
| SCHEMBL12748241 | 0.90 | TSPO (0.44) | TSPO | |
| SCHEMBL416930 | 0.89 | TSPO (0.54) | TSPO | |
| SCHEMBL6693579 | 0.86 | FABP4 (0.44) | TSPO | |
| SCHEMBL416598 | 0.85 | TSPO (0.42) | TSPO | |
| SCHEMBL30106112 | 0.82 | TSPO (0.77) | TSPO | |
| SCHEMBL419235 | 0.82 | TSPO (0.77) | TSPO | |
| Hydrochloric Acid SCHEMBL28410959 | 0.82 | TSPO (0.75) | TSPO | |
| SCHEMBL12748246 | 0.79 | TSPO (0.43) | TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110229093-B | Carbazole compounds for in vivo imaging | 通用电气健康护理有限公司 | 2022-12-13 | — | — | CN | disclosed |
| EP-2411362-B1 | Tricyclic indole derivatives as PBR ligands | GE HEALTHCARE LTD (GB) | 2017-05-31 | — | — | EP | disclosed |
| EP-2411362-A2 | INDOLE DERIVATIVES | GE Healthcare UK Limited (GB) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010109007-A2 | INDOLE DERIVATIVES | GE HEALTHCARE LIMITED (GB) | 2010-09-30 | — | — | WO | disclosed |