⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31556684 | 1.00 | — | — | |
| SCHEMBL1659134 | 0.74 | — | — | |
| SCHEMBL833937 | 0.69 | — | — | |
| SCHEMBL29404525 | 0.67 | — | — | |
| SCHEMBL29314 | 0.67 | — | — | |
| SCHEMBL1446040 | 0.67 | LMNA (0.39) | — | |
| SCHEMBL31463495 | 0.67 | — | — | |
| Iodide SCHEMBL8772817 | 0.67 | TSHR (0.47) | — | |
| Bromide SCHEMBL164660 | 0.67 | TSHR (0.47) | — | |
| SCHEMBL170136 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| US-20240166642-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-05-23 | — | — | US | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |
| EP-1582524-B1 | Method of preparing organomagnesium compounds | UNIV MUENCHEN L MAXIMILIANS (DE) | 2008-08-13 | — | — | EP | disclosed |
| US-7387751-B2 | Method of preparing organomagnesium compounds | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2008-06-17 | — | — | US | disclosed |
| US-7384580-B2 | Method of preparing organomagnesium compounds | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2008-06-10 | — | — | US | disclosed |
| US-20070194468-A1 | Method of preparing organomagnesium compounds | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2007-08-23 | — | — | US | disclosed |
| US-20050218532-A1 | Method of preparing organomagnesium compounds | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2005-10-06 | — | — | US | disclosed |
| EP-1582524-A1 | Method of preparing organomagnesium compounds | Ludwig Maximilians Universität (DE) | 2005-10-05 | — | — | EP | disclosed |
| EP-1582523-A1 | Method of preparing organomagnesium compounds | Ludwig-Maximilians-Universität München (DE) | 2005-10-05 | — | — | EP | disclosed |