Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ME2 | P23368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4803794 | 0.94 | EPHX1 (0.52) | EPHX1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL14277076 | 0.80 | CYP1A2 (0.53) | EPHX1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL29569823 | 0.77 | ALDH1A1 (0.50) | KMT2AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL12630636 | 0.76 | EPHX1 (0.43) | EPHX1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL14277073 | 0.75 | EPHX1 (0.56) | EPHX1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL4648309 | 0.73 | TDP1 (0.56) | EPHX1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL3292664 | 0.72 | EPHX1 (0.54) | EPHX1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL111606 | 0.72 | EPHX1 (0.54) | EPHX1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL31326117 | 0.72 | EPHX1 (0.54) | EPHX1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL2222008 | 0.72 | EPHX1 (0.54) | EPHX1KDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368512-B2 | Detection and functionalization of dendrimers | UNIVERSITY OF SOUTH FLORIDA (US) | 2008-05-06 | — | — | US | disclosed |
| US-20050008571-A1 | Detection and functionalization of dendrimers | NEWKOME GEORGE (US) | 2005-01-13 | — | — | US | disclosed |