Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20987083 | 0.88 | KDM1A (0.51) | KDM1AHDAC1MAP4K4SMN1; SMN2CA1 | |
| SCHEMBL5904086 | 0.87 | CHEK2 (0.59) | KDM1AHDAC1MAP4K4CA1CA2 | |
| SCHEMBL20885803 | 0.83 | MAP4K4 (0.55) | KDM1AHDAC1MAP4K4SMN1; SMN2CA1 | |
| SCHEMBL20885652 | 0.83 | MAP4K4 (0.55) | KDM1AHDAC1MAP4K4SMN1; SMN2CA1 | |
| SCHEMBL20885881 | 0.82 | MALT1 (0.55) | KDM1AHDAC1MAP4K4SMN1; SMN2CA1 | |
| SCHEMBL28414233 | 0.81 | MALT1 (0.57) | KDM1AHDAC1CA1CA2MALT1 | |
| SCHEMBL20885643 | 0.81 | MAP4K4 (0.53) | KDM1AHDAC1MAP4K4SMN1; SMN2CA1 | |
| SCHEMBL4678205 | 0.81 | AKT1 (0.54) | MAP4K4SMN1; SMN2KDM5AKDM4CKDM5B | |
| SCHEMBL20885878 | 0.81 | HDAC1 (0.62) | KDM1AHDAC1MAP4K4SMN1; SMN2MALT1 | |
| SCHEMBL20885879 | 0.80 | KDM1A (0.53) | KDM1AHDAC1MAP4K4SMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7345059-B2 | Diphenylpyridine derivatives, preparation and therapeutic application thereof | SANOFI-AVENTIS (FR) | 2008-03-18 | — | — | US | disclosed |
| US-20060189664-A1 | Diphenylpyridine derivatives, preparation and therapeutic application thereof | SANOFI-AVENTIS (FR) | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189664-A1 | Diphenylpyridine derivatives, preparation and therapeutic application thereof | CNR1, HDAC10, AKR1B10 | KDM1A 1576/4885HDAC1 134/4885MAP4K4 4114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.