Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 4/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22722197 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KMT2AKDM4EHPGDCYP1A2 | |
| SCHEMBL22989201 | 0.75 | KDM4E (0.49) | ALDH1A1KMT2AKDM4EHPGDCYP1A2 | |
| SCHEMBL12177611 | 0.74 | ALDH1A1 (0.48) | ALDH1A1KMT2AKDM4EHPGDCYP1A2 | |
| SCHEMBL15856051 | 0.73 | ALDH1A1 (0.57) | ALDH1A1KMT2AKDM4EHPGDCYP1A2 | |
| SCHEMBL29350533 | 0.72 | HSD17B10 (0.64) | ALDH1A1KMT2AKDM4EHPGDCYP1A2 | |
| SCHEMBL242958 | 0.72 | HSD17B10 (0.64) | ALDH1A1KMT2AKDM4EHPGDCYP1A2 | |
| Hydrochloric Acid SCHEMBL8600808 | 0.71 | HSD17B10 (0.62) | ALDH1A1KMT2AKDM4EHPGDCYP1A2 | |
| Ammonia Solution, Strong SCHEMBL31590520 | 0.71 | HSD17B10 (0.62) | ALDH1A1KMT2AKDM4EHPGDCYP1A2 | |
| SCHEMBL29537012 | 0.71 | ALDH1A1 (0.57) | ALDH1A1KMT2AKDM4EHPGDCYP1A2 | |
| SCHEMBL28673575 | 0.71 | HSD17B10 (0.62) | ALDH1A1KMT2AKDM4EHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7355037-B2 | Thermolabile hydroxyl protecting groups and methods of use | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2008-04-08 | — | — | US | disclosed |
| US-20050020827-A1 | Thermolabile hydroxyl protecting groups and methods of use | GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2005-01-27 | — | — | US | disclosed |
| WO-2003048179-A2 | THERMOLABILE HYDROXYL PROTECTING GROUPS AND METHODS OF USE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020827-A1 | Thermolabile hydroxyl protecting groups and methods of use | ADH1A, NR2C2, NR1H2 | ALDH1A1 200/4885KMT2A 944/4885KDM4E 2464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.