Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28183398 | 0.82 | TSHR (0.38) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL22572647 | 0.80 | TSHR (0.42) | TSHRHPGDTHRB | |
| SCHEMBL22572579 | 0.80 | TSHR (0.42) | TSHRHPGDTHRB | |
| SCHEMBL6935317 | 0.79 | ALDH1A1 (0.33) | ALDH1A1HSD17B10 | |
| SCHEMBL21433560 | 0.79 | TSHR (0.38) | TSHRHPGD | |
| SCHEMBL21633819 | 0.78 | — | — | |
| SCHEMBL27729290 | 0.78 | TSHR (0.35) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27778296 | 0.78 | TSHR (0.52) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27718503 | 0.78 | TSHR (0.43) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL28177426 | 0.77 | NPSR1 (0.47) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368430-B1 | DENTAL AND MEDICAL POLYMER COMPOSITES AND COMPOSITIONS | STICK TECH OY (FI) | 2008-09-10 | — | — | EP | disclosed |
| US-7354969-B2 | Dental and medical polymer composites and compositions | STICK TECH OY (FI) | 2008-04-08 | — | — | US | disclosed |
| US-20040097627-A1 | Dental and medical polymer composites and compositions | STICK TECH OY (FI) | 2004-05-20 | — | — | US | disclosed |
| EP-1368430-A1 | DENTAL AND MEDICAL POLYMER COMPOSITES AND COMPOSITIONS | Vallittu, Pekka (FI) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002062901-A1 | DENTAL AND MEDICAL POLYMER COMPOSITES AND COMPOSITIONS | VALLITTU PEKKA (FI) | 2002-08-15 | — | — | WO | disclosed |
| US-5886064-A | A CURABLE DENTAL COMPOSITION COMPRISING AN UNSATURATED MONOMER, A POLYMERIZATION INITITATOR, FILLER AND DENDRIMER HAVING UNSATURATED END GROUPS | IVOCLAR AG (LI) | 1999-03-23 | — | — | US | disclosed |