Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 11/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27569910 | 0.93 | TSHR (0.58) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL12984317 | 0.87 | THRB (0.42) | TSHRALDH1A1HSD17B10HPGDTHRB | |
| SCHEMBL27718503 | 0.86 | TSHR (0.43) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL8382801 | 0.83 | TSHR (0.59) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL25431935 | 0.83 | TSHR (0.57) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL4606584 | 0.83 | TSHR (0.53) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL1532813 | 0.81 | THRB (0.58) | TSHRALDH1A1THRBCYP2D6CYP2C19 | |
| SCHEMBL27892963 | 0.81 | TSHR (0.55) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL25234307 | 0.81 | TSHR (0.49) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL11096534 | 0.81 | TSHR (0.56) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101528603-B | Mesoporous silica particles | KAO CORP. (JP) | 2012-02-08 | — | — | CN | disclosed |
| CN-101528603-A | Mesoporous silica particles | KAO CORP (JP) | 2009-09-09 | — | — | CN | disclosed |