SCHEMBL4805637

SCHEMBL4805637

C=C(C(=O)O)c1ccc(-c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.52
RXRA P19793 3/20 0.51
RXRB P28702 3/20 0.51
RXRG P48443 1/20 0.51
HDAC1 Q13547 1/20 0.48
RARB P10826 1/20 0.47
RARG P13631 1/20 0.47
KIF11 P52732 1/20 0.46
EPHX2 P34913 1/20 0.45
NR1H4 Q96RI1 1/20 0.45
PTGES O14684 1/20 0.45
ALOX5 P09917 1/20 0.45
NQO2 P16083 1/20 0.44
RAB9A P51151 2/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HTT P42858 1/20 0.43
KMT2A Q03164 1/20 0.43
HIF1A Q16665 1/20 0.43
NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4578492 0.94 SRD5A2 (0.57) SRD5A2HDAC1RARBRARGEPHX2
SCHEMBL19026597 0.84 MAPT (0.44) RXRARXRBRAB9AMEN1KMT2A
SCHEMBL29869060 0.81 CES2 (0.53) SRD5A2RXRARXRBRXRGKIF11
SCHEMBL16595419 0.81 SRD5A2 (0.55) SRD5A2RXRARXRBRXRGHDAC1
SCHEMBL2053275 0.80 SRD5A2 (0.77) SRD5A2RXRARXRBRXRGHDAC1
SCHEMBL4801712 0.79 MAPT (0.63) KIF11RAB9AMEN1ALDH1A1KMT2A
SCHEMBL4797412 0.79 ALDH1A1 (0.52) SRD5A2RXRARXRBHDAC1KIF11
SCHEMBL29849872 0.78 MAPT (0.50) SRD5A2RXRARXRBHDAC1RAB9A
SCHEMBL31425654 0.78 SMN1; SMN2 (0.50) RXRARXRBRXRGRAB9AMEN1
SCHEMBL36308 0.78 SMN1; SMN2 (0.56) RAB9AMEN1ALDH1A1KMT2AHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7416821-B2 Thermally cured undercoat for lithographic application FUJIFILM ELECTRONIC MATERIALS, U.S.A., INC. (US) 2008-08-26 US disclosed
EP-1743363-A2 THERMALLY CURED UNDERCOAT FOR LITHOGRAPHIC APPLICATION FujiFilm Electronic Materials USA, Inc. (US) 2007-01-17 EP disclosed
US-20050238997-A1 Thermally cured undercoat for lithographic application FUJIFILM ELECTRONIC MATERIALS, U.S.A., INC. 2005-10-27 US disclosed
WO-2005089150-A2 THERMALLY CURED UNDERCOAT FOR LITHOGRAPHIC APPLICATION FUJIFILM ELECTRONIC MATERIALS USA INC. (US) 2005-09-29 WO disclosed