Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.66 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3191789 | 0.87 | S100A4 (0.61) | S100A4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28041851 | 0.86 | S100A4 (0.50) | S100A4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9672404 | 0.83 | S100A4 (0.50) | S100A4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9621885 | 0.80 | S100A4 (0.83) | S100A4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29849465 | 0.80 | S100A4 (0.83) | S100A4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10694724 | 0.80 | S100A4 (0.47) | S100A4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL11132864 | 0.80 | S100A4 (0.51) | S100A4GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27280773 | 0.79 | S100A4 (0.50) | S100A4GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL11753500 | 0.78 | S100A4 (0.49) | S100A4GRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL11753496 | 0.78 | S100A4 (0.49) | S100A4GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178948-B1 | NOVEL POLYUREA- AND/OR POLYURETHANE-POLYORGANOSILOXANE COMPOUNDS | MOMENTIVE PERFORMANCE MAT GMBH (DE) | 2017-04-05 | — | — | EP | disclosed |
| EP-2129704-B1 | NOVEL POLYAMIDE-POLYSILOXANE COMPOUNDS | MOMENTIVE PERFORMANCE MAT INC (DE) | 2016-01-06 | — | — | EP | disclosed |
| US-8785587-B2 | Polyurea- and/or polyurethane-polyorganosiloxane compounds | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2014-07-22 | — | — | US | disclosed |
| US-8742053-B2 | Polyamide-polysiloxane compounds | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2014-06-03 | — | — | US | disclosed |
| US-8673985-B2 | Polycarbonate-polyorganosiloxane- and/or polyurethane-polyorganosiloxane compounds | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| US-8491879-B2 | Ammonium-polyurethane- and/or polycarbonate compounds | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2013-07-23 | — | — | US | disclosed |
| US-8410236-B2 | Polycarbonate and/or polyurethane polyorganosiloxane compounds | Momentive Performance Matierals GmbH (DE) | 2013-04-02 | — | — | US | disclosed |
| EP-2257586-B1 | NOVEL POLYCARBONATE POLYORGANOSILOXANE AND/OR POLYURETHANE POLYORGANOSILOXANE COMPOUNDS | MOMENTIVE PERFORMANCE MAT INC (DE) | 2012-02-01 | — | — | EP | disclosed |
| EP-2257585-B1 | NOVEL AMMONIUM POLYURETHANE AND/OR POLYCARBONATE COMPOUNDS | MOMENTIVE PERFORMANCE MAT INC (DE) | 2011-11-09 | — | — | EP | disclosed |
| US-20110182844-A1 | Novel Polyurea- and/or Polyurethane-Polyorganosiloxane Compounds | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2011-07-28 | — | — | US | disclosed |
| US-20110039948-A1 | Novel Polycarbonate-Polyorganosiloxane- And/Or Polyurethane-Polyorganosiloxane Compounds | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2011-02-17 | — | — | US | disclosed |
| US-20110033411-A1 | Novel Ammonium-Polyurethane- And/Or Polycarbonate Compounds | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2011-02-10 | — | — | US | disclosed |
| US-20100210809-A1 | Polycarbonate And/Or Polyurethane Polyorganosiloxane Compounds | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2010-08-19 | — | — | US | disclosed |
| US-20100178266-A1 | Process For The Manufacture Of Polyorganosiloxanes Comprising (C6-C60)-Alkylmethylsiloxy Groups And Dimethylsiloxy Groups | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2010-07-15 | — | — | US | disclosed |
| EP-2178948-A1 | NOVEL POLYUREA- AND/OR POLYURETHANE-POLYORGANOSILOXANE COMPOUNDS | Momentive Performance Materials GmbH (DE) | 2010-04-28 | — | — | EP | disclosed |
| EP-2164891-A1 | PROCESS FOR THE MANUFACTURE OF POLYORGANOSILOXANES COMPRISING (C6-C60)-ALKYLMETHYLSILOXY GROUPS AND DIMETHYLSILOXY GROUPS | Momentive Performance Materials GmbH (DE) | 2010-03-24 | — | — | EP | disclosed |
| US-20100044615-A1 | Novel Polyamide-Polysiloxane Compounds | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2010-02-25 | — | — | US | disclosed |
| WO-2009021989-A1 | NOVEL POLYUREA- AND/OR POLYURETHANE-POLYORGANOSILOXANE COMPOUNDS | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2009-02-19 | — | — | WO | disclosed |
| WO-2009003862-A1 | PROCESS FOR THE MANUFACTURE OF POLYORGANOSILOXANES COMPRISING (C6-C60)-ALKYLMETHYLSILOXY GROUPS AND DIMETHYLSILOXY GROUPS | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2009-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100044615-A1 | Novel Polyamide-Polysiloxane Compounds | PUF60, MUS81, PARG | S100A4 4457/4885GRIN2D 2300/4885GRIN3B 2269/4885 |
| US-20110039948-A1 | Novel Polycarbonate-Polyorganosiloxane- And/Or Polyurethane-Polyorganosiloxane Compounds | PUF60, ERCC4, XRCC5 | S100A4 4082/4885GRIN2D 4874/4885GRIN3B 4875/4885 |
| US-20110033411-A1 | Novel Ammonium-Polyurethane- And/Or Polycarbonate Compounds | PUF60, DDX3X, ATL3 | S100A4 4589/4885GRIN2D 4059/4885GRIN3B 3663/4885 |
| US-20110182844-A1 | Novel Polyurea- and/or Polyurethane-Polyorganosiloxane Compounds | PUF60, PBRM1, UFM1 | S100A4 4826/4885GRIN2D 4867/4885GRIN3B 4877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.