SCHEMBL4805653

SCHEMBL4805653

C=C(CCCC)C(=O)OC(=O)C(C)=CC

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.37
CES1 P23141 3/20 0.36
CES2 O00748 2/20 0.35
ALDH1A1 P00352 4/20 0.33
TP53 P04637 1/20 0.33
CA1 P00915 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B3 P37058 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6916133 0.87 CES1 (0.46) TSHRCES1CES2ALDH1A1TP53
SCHEMBL10527168 0.85 TSHR (0.34) TSHRCES1CES2ALDH1A1TP53
SCHEMBL6067659 0.85 TSHR (0.34) TSHRCES1CES2ALDH1A1TP53
SCHEMBL2483865 0.83 TSHR (0.48) TSHRCES1CES2ALDH1A1TP53
SCHEMBL156660 0.83 TDP1 (0.32) TSHRALDH1A1
SCHEMBL6057358 0.83 CES1 (0.42) TSHRCES1CES2ALDH1A1TP53
SCHEMBL3862259 0.83 CES1 (0.42) TSHRCES1CES2ALDH1A1TP53
SCHEMBL17453333 0.82 TSHR (0.34) TSHRCES1CES2HPGD
SCHEMBL9743325 0.81 CES1 (0.41) TSHRCES1CES2ALDH1A1TP53
SCHEMBL9534599 0.81 CES2 (0.48) TSHRCES1CES2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6673500-B1 Document security processes XEROX CORPORATION 2004-01-06 US claimed
WO-2024102687-A1 HIGH RESILIENT THERMOPLASTIC POLYURETHANES AND USES THEREOF LUBRIZOL ADVANCED MATERIALS, INC. (US) 2024-05-16 WO disclosed
US-11976159-B2 Articles made from hydrophilic thermoplastic polyurethane compositions LUBRIZOL ADVANCED MATERIALS, INC. (US) 2024-05-07 US disclosed
US-20240043603-A1 THERMOPLASTIC POLYURETHANES WITH HIGH MOISTURE VAPOR TRANSMISSION AND LOW WATER ABSORPTION LUBRIZOL ADVANCED MATERIALS, INC. (US) 2024-02-08 US disclosed
WO-2023239891-A1 THERMOPLASTIC POLYURETHANES WITH HIGH TEMPERATURE STABILITY AND USES THEREOF LUBRIZOL ADVANCED MATERIALS, INC. (US) 2023-12-14 WO disclosed
US-20230382015-A1 Method of Making Articles from Recyclable Fabrics LUBRIZOL ADVANCED MATERIALS, INC. (US) 2023-11-30 US disclosed
US-11827737-B2 Thermoplastic polyurethanes with high moisture vapor transmission and low water absorption LUBRIZOL ADVANCED MATERIALS, INC. (US) 2023-11-28 US disclosed
US-20230374193-A1 MELT-SPUN THERMOPLASTIC POLYURETHANE FIBER LUBRIZOL ADVANCED MATERIALS, INC. (US) 2023-11-23 US disclosed
US-20230366131-A1 DYEABLE FABRIC COMPRISING MELT-SPUN THERMOPLASTIC POLYURETHANE FIBERS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2023-11-16 US disclosed
EP-4237605-A1 MELT-SPUN THERMOPLASTIC POLYURETHANE FIBER Lubrizol Advanced Materials, Inc. (US) 2023-09-06 EP disclosed
US-7052730-B2 Document security processes XEROX CORPORATION (US) 2006-05-30 US disclosed
US-20050043483-A1 Polyester molding composition GENERAL ELECTRIC COMPANY 2005-02-24 US disclosed
EP-1508593-A1 Polyester molding composition GENERAL ELECTRIC COMPANY (US) 2005-02-23 EP disclosed
US-20040037947-A1 Document security processes XEROX CORPORATION 2004-02-26 US disclosed
US-6673500-B1 Document security processes XEROX CORPORATION 2004-01-06 US disclosed
EP-0961171-A1 Photoimageable composition having improved flexibility Nichigo-Morton Co Ltd (JP) 1999-12-01 EP disclosed
US-5242888-A Ink receptor ARKWRIGHT, INCORPORATED (US) 1993-09-07 US disclosed
US-5219933-A Butadiene rubber substrate with grafted rigid phase of methyl methacrylate homo- or copolymer THE DOW CHEMICAL COMPANY (US) 1993-06-15 US disclosed
US-4677150-A AROMATIC POLYESTER CARBONATES IMPACT MODIFIERS CELANESE ENGINEERING RESINS INC. (US) 1987-06-30 US disclosed
US-4607075-A AROMATIC POLYESTER AND IMPACT MODIFIER OF BUTADIENE CORE-SHELL COPOLYMERS; MOLDING COMPOSITIONS GAF CORPORATION (US) 1986-08-19 US disclosed