Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.59 |
| ▸ | CA7 | P43166 | 3/20 | 0.59 |
| ▸ | CA9 | Q16790 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11227119 | 0.83 | CA12 (0.47) | CA12CA14CA7CA9TSHR | |
| SCHEMBL28349586 | 0.83 | TSHR (0.50) | CA12CA14CA7CA9TSHR | |
| SCHEMBL19248813 | 0.82 | CA12 (0.46) | CA12CA14CA7CA9TSHR | |
| SCHEMBL7428536 | 0.82 | MGAM (0.46) | CA12CA14CA7CA9SCN1A | |
| SCHEMBL72889 | 0.81 | TSHR (0.67) | CA12CA14CA7CA9TSHR | |
| SCHEMBL13995401 | 0.81 | CA12 (0.49) | CA12CA14CA7CA9TSHR | |
| SCHEMBL17725604 | 0.81 | TSHR (0.48) | CA12CA14CA7CA9TSHR | |
| SCHEMBL9098228 | 0.80 | CA7 (0.41) | CA12CA14CA7CA9SCN1A | |
| Hydrochloric Acid SCHEMBL10588527 | 0.80 | CA12 (0.45) | CA12CA14CA7CA9TSHR | |
| Hydrochloric Acid SCHEMBL7567529 | 0.80 | MGAM (0.45) | CA12CA14CA7CA9SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-20230357158-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2023-11-09 | — | — | US | disclosed |
| WO-2023168367-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2023-09-07 | — | — | WO | disclosed |
| US-7371807-B2 | Blocked biuretized isocyanates | BAYER MATERIALSCIENCE LLC (US) | 2008-05-13 | — | — | US | disclosed |
| EP-1650245-B1 | Biuretized polyisocyanates blocked with aralkylamines | BAYER MATERIALSCIENCE LLC (US) | 2007-12-19 | — | — | EP | disclosed |
| US-20060089479-A1 | Blocked biuretized isocyanates | COVESTRO LLC | 2006-04-27 | — | — | US | disclosed |
| EP-1650245-A1 | Biuretized polyisocyanates blocked with aralkylamines | Bayer MaterialScience LLC (US) | 2006-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | CGAS, GLS2, GLS | CA12 3267/4885CA14 3425/4885CA7 1625/4885 |
| US-20230357158-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | CGAS, GLS2, GLS | CA12 3267/4885CA14 3425/4885CA7 1625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.