Acrylic Acid

Acrylic Acid

SCHEMBL4806645

C=C(C(=O)O)c1ccc(Cl)cc1.C=CC(=O)O

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.48
TSHR P16473 1/20 0.48
CES2 O00748 3/20 0.45
CES1 P23141 3/20 0.45
SRD5A2 P31213 1/20 0.44
ERCC5 P28715 1/20 0.43
FEN1 P39748 1/20 0.43
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
ALDH1A1 P00352 3/20 0.40
HTT P42858 1/20 0.40
CYP1B1 Q16678 1/20 0.40
GSK3B P49841 2/20 0.39
MAPK1 P28482 2/20 0.39
LMNA P02545 2/20 0.39
MAPT P10636 3/20 0.38
KDM4E B2RXH2 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
MEN1 O00255 1/20 0.38
EGFR P00533 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL126170 0.90 ALOX15 (0.58) ALOX15TSHRCES2CES1SRD5A2
Hydrochloric Acid SCHEMBL27445697 0.88 ALOX15 (0.56) ALOX15TSHRCES2CES1SRD5A2
SCHEMBL4805938 0.84 ALOX15 (0.52) ALOX15TSHRCES2CES1SRD5A2
4-Chloro-Benzoic Acid SCHEMBL27869595 0.82 TSHR (0.74) ALOX15TSHRCES2CES1SRD5A2
Acrylic Acid SCHEMBL7211404 0.82 AKT1 (0.56) ALOX15TSHRCES2CES1CA1
Acrylic Acid SCHEMBL6862448 0.81 ALDH1A1 (0.48) CES2CES1SRD5A2ALDH1A1HTT
SCHEMBL713716 0.78 TSHR (0.47) ALOX15TSHRCES2CES1SRD5A2
Chlorobenzene SCHEMBL27335147 0.74 TSHR (0.55) ALOX15TSHRCES2CES1ALDH1A1
Acrylic Acid SCHEMBL29152405 0.74 TSHR (0.52) ALOX15TSHRCA1CA2ALDH1A1
SCHEMBL14938477 0.74 ALDH1A1 (0.48) ALOX15TSHRALDH1A1HTTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7345134-B2 Crosslinked polymers with low loss and tunable refractive indices LUMERA CORPORATION (US) 2008-03-18 US disclosed
US-7262230-B2 Process of preparing crosslinked, low loss polymers with tunable refractive indices LUMERA CORPORATION (US) 2007-08-28 US disclosed
US-7231127-B2 Waveguide devices with low loss clads and tunable refractive indices LUMERA CORPORATION (US) 2007-06-12 US disclosed
US-20060165369-A1 Electrode, and a polymer clad of a polymer of halocatechol diacrylate, haloresorcinol diacrylate, or a halohydroquinone diacrylate, and a polymer core; clad containing a hole transporter of diarylamine or a carbazole SILICON VALLEY BANK 2006-07-27 US disclosed
US-20060167212-A1 Crosslinked polymers with low loss and tunable refractive indices SILICON VALLEY BANK 2006-07-27 US disclosed
US-20060167213-A1 Process of preparing crosslinked, low loss polymers with tunable refractive indices SILICON VALLEY BANK 2006-07-27 US disclosed