Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.49 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48068 | 1.00 | CYP19A1 (0.49) | CYP19A1CYP11B1CYP11B2MAPTMEN1 | |
| SCHEMBL10633557 | 0.92 | PTGDR2 (0.49) | CYP19A1CYP11B1CYP11B2MAPTMEN1 | |
| SCHEMBL48067 | 0.92 | CYP19A1 (0.49) | CYP19A1CYP11B1CYP11B2MAPTMEN1 | |
| SCHEMBL11110381 | 0.89 | RECQL (0.53) | CYP19A1CYP11B1CYP11B2MAPTMEN1 | |
| SCHEMBL7414457 | 0.88 | CYP19A1 (0.55) | CYP19A1CYP11B1CYP11B2MAPTMEN1 | |
| SCHEMBL6595337 | 0.88 | ALDH1A1 (0.45) | CYP19A1CYP11B1CYP11B2MAPTMEN1 | |
| SCHEMBL6595335 | 0.88 | ALDH1A1 (0.45) | CYP19A1CYP11B1CYP11B2MAPTMEN1 | |
| SCHEMBL29570634 | 0.88 | MITF (0.45) | CYP19A1CYP11B1CYP11B2MAPTMEN1 | |
| SCHEMBL7415724 | 0.88 | CYP19A1 (0.55) | CYP19A1CYP11B1CYP11B2MAPTMEN1 | |
| SCHEMBL27576402 | 0.87 | CYP19A1 (0.47) | CYP19A1MAPTMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025036307-A1 | APPLICATION OF ANTI-FRα ANTIBODY-DRUG CONJUGATE IN TREATMENT OF DISEASES | 百奥泰生物制药股份有限公司 | 2025-02-20 | — | — | WO | disclosed |
| CN-114957053-B | Oxoethylene compound or pharmaceutically acceptable salt thereof, preparation method and application thereof, pharmaceutical composition and application thereof | 中国医学科学院医药生物技术研究所 | 2023-12-22 | — | — | CN | disclosed |
| WO-2023155808-A1 | CONJUGATE OF ANTIBODY-ERIBULIN OR DERIVATIVE THEREOF, INTERMEDIATE THEREOF, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 苏州宜联生物医药有限公司 | 2023-08-24 | — | — | WO | disclosed |
| CN-114957053-A | Oxoethylene compound or pharmaceutically acceptable salt thereof, preparation method and application thereof, pharmaceutical composition and application thereof | 中国医学科学院医药生物技术研究所 | 2022-08-30 | — | — | CN | disclosed |
| EP-2149586-B1 | AMINE EPOXY RESIN CURING AGENT, GAS BARRIER EPOXY RESIN COMPOSITION COMPRISING THE CURING AGENT, COATING AGENT, AND ADHESIVE AGENT FOR LAMINATE | MITSUBISHI GAS CHEMICAL CO (JP) | 2018-01-03 | — | — | EP | disclosed |
| US-8128782-B2 | Amine epoxy resin curing agent, gas barrier epoxy resin composition comprising the curing agent, coating agent, and adhesive agent for laminate | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20100160494-A1 | AMINE EPOXY RESIN CURING AGENT, GAS BARRIER EPOXY RESIN COMPOSITION COMPRISING THE CURING AGENT, COATING AGENT, AND ADHESIVE AGENT FOR LAMINATE | MITSUBISHI GAS CHEMICAL COMPANY INC. (JP) | 2010-06-24 | — | — | US | disclosed |
| EP-2149586-A1 | AMINE EPOXY RESIN CURING AGENT, GAS BARRIER EPOXY RESIN COMPOSITION COMPRISING THE CURING AGENT, COATING AGENT, AND ADHESIVE AGENT FOR LAMINATE | Mitsubishi Gas Chemical Company, Inc. (JP) | 2010-02-03 | — | — | EP | disclosed |
| US-6815542-B2 | Nucleoside compounds and uses thereof | RIBAPHARM, INC. | 2004-11-09 | — | — | US | disclosed |
| US-20040002596-A1 | Nucleoside compounds and uses thereof | TECHNOLAS PERFECT VISION GMBH (DE) | 2004-01-01 | — | — | US | disclosed |
| US-6649652-B2 | Hypotensive agents; hyperglycemic agents | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2003-11-18 | — | — | US | disclosed |
| US-20030092755-A1 | Novel prodrugs for antimicrobial amidines | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-05-15 | — | — | US | disclosed |
| US-5854212-A | Cyclohexapeptidyl bisamine compound, compositions containing said compound and methods of use | MERCK & CO., INC. (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0862579-A1 | CYCLOHEXAPEPTIDYL BISAMINE COMPOUND, COMPOSITIONS CONTAINING SAID COMPOUND AND METHODS OF USE | Merck & Co., Inc. (US) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997017365-A1 | CYCLOHEXAPEPTIDYL BISAMINE COMPOUND, COMPOSITIONS CONTAINING SAID COMPOUND AND METHODS OF USE | MERCK & CO., INC. (US) | 1997-05-15 | — | — | WO | disclosed |
| US-4125706-A | Novel process for the preparation of 1-N-(alpha-substituted-omega-aminoacyl)-3'-deoxyribostamycin | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1978-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002596-A1 | Nucleoside compounds and uses thereof | PNP, SLC29A1, SLC29A2 | CYP19A1 3087/4885CYP11B1 2339/4885CYP11B2 2139/4885 |
| US-20030092755-A1 | Novel prodrugs for antimicrobial amidines | NR1H3, APEH, NR1H2 | CYP19A1 1346/4885CYP11B1 1144/4885CYP11B2 1156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.