Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | HSD3B1 | P14060 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564985 | 0.96 | CYP19A1 (0.34) | CYP19A1MBOAT4GRIN1GRIN2BLMNA | |
| SCHEMBL8571736 | 0.96 | CYP19A1 (0.34) | CYP19A1MBOAT4GRIN1GRIN2BLMNA | |
| SCHEMBL4807027 | 0.82 | CYP19A1 (0.41) | CYP19A1MBOAT4GRIN1GRIN2BLMNA | |
| SCHEMBL7643432 | 0.82 | CYP19A1 (0.41) | CYP19A1MBOAT4GRIN1GRIN2BLMNA | |
| SCHEMBL11410578 | 0.81 | CYP19A1 (0.38) | CYP19A1MBOAT4GRIN1GRIN2BLMNA | |
| SCHEMBL8823382 | 0.80 | SRD5A2 (0.39) | CYP19A1MBOAT4GRIN1GRIN2BLMNA | |
| SCHEMBL8823386 | 0.80 | SRD5A2 (0.39) | CYP19A1MBOAT4GRIN1GRIN2BLMNA | |
| SCHEMBL9318599 | 0.79 | CYP19A1 (0.39) | CYP19A1MBOAT4GRIN1GRIN2BLMNA | |
| SCHEMBL5580932 | 0.79 | MBOAT4 (0.41) | CYP19A1MBOAT4G6PDGRIN1GRIN2B | |
| SCHEMBL9618179 | 0.77 | SRD5A1 (0.42) | CYP19A1MBOAT4GRIN1GRIN2BSRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2462936-A1 | SiRNA mediated post-transriptional gene-silencing of genes involved in alopecia | Gencia Corporation (US) | 2012-06-13 | — | — | EP | claimed |
| US-20070141009-A1 | Sirna mediated post-transriptional gene silencing of genes involved in alopecia | GENCIA CORPORATION | 2007-06-21 | — | — | US | claimed |
| EP-2462936-A1 | SiRNA mediated post-transriptional gene-silencing of genes involved in alopecia | Gencia Corporation (US) | 2012-06-13 | — | — | EP | disclosed |
| US-20070141009-A1 | Sirna mediated post-transriptional gene silencing of genes involved in alopecia | GENCIA CORPORATION | 2007-06-21 | — | — | US | disclosed |
| US-5670643-A | Method for preparing finasteride | GLAXO WELLCOME INC. (US) | 1997-09-23 | — | — | US | disclosed |