Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLD1 | Q13393 | 13/20 | 0.59 |
| ▸ | PLD2 | O14939 | 12/20 | 0.59 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | CCR1 | P32246 | 2/20 | 0.51 |
| ▸ | YEATS4 | O95619 | 1/20 | 0.48 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.48 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | YEATS2 | Q9ULM3 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6697552 | 0.95 | PLD2 (0.57) | PLD1PLD2OPRL1CCR1OPRM1 | |
| SCHEMBL4805878 | 0.95 | PLD2 (0.57) | PLD1PLD2OPRL1CCR1OPRM1 | |
| SCHEMBL4805869 | 0.95 | PLD2 (0.57) | PLD1PLD2OPRL1CCR1OPRM1 | |
| SCHEMBL4850139 | 0.93 | PLD1 (0.59) | PLD1PLD2OPRL1DRD2CCR1 | |
| SCHEMBL4808944 | 0.91 | OPRL1 (0.57) | PLD1PLD2OPRL1DRD2CCR1 | |
| Hydrochloric Acid SCHEMBL4805706 | 0.90 | OPRL1 (0.56) | PLD1PLD2OPRL1DRD2CCR1 | |
| SCHEMBL4807222 | 0.90 | PLD2 (0.56) | PLD1PLD2OPRL1CCR1OPRM1 | |
| SCHEMBL6628489 | 0.90 | OPRL1 (0.60) | PLD1PLD2OPRL1DRD2CCR1 | |
| Hydrochloric Acid SCHEMBL4805718 | 0.90 | OPRL1 (0.56) | PLD1PLD2OPRL1DRD2CCR1 | |
| SCHEMBL4807214 | 0.90 | PLD2 (0.56) | PLD1PLD2OPRL1CCR1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388020-B2 | Benzimidazol derivatives modulate chemokine receptors | ASTRAZENECA AB (SE) | 2008-06-17 | — | — | US | claimed |
| US-20040116435-A1 | Benzimidazol derivatives modulate chemokine receptors | ASTRAZENECA AB (SE) | 2004-06-17 | — | — | US | claimed |
| EP-1373248-A1 | BENZIMIDAZOL DERIVATIVES MODULATE CHEMOKINE RECEPTORS | AstraZeneca AB (SE) | 2004-01-02 | — | — | EP | claimed |
| WO-2002074763-A1 | BENZIMIDAZOL DERIVATIVES MODULATE CHEMOKINE RECEPTORS | ASTRAZENECA AB (SE) | 2002-09-26 | — | — | WO | claimed |
| US-7388020-B2 | Benzimidazol derivatives modulate chemokine receptors | ASTRAZENECA AB (SE) | 2008-06-17 | — | — | US | disclosed |
| US-20040116435-A1 | Benzimidazol derivatives modulate chemokine receptors | ASTRAZENECA AB (SE) | 2004-06-17 | — | — | US | disclosed |
| EP-1373248-A1 | BENZIMIDAZOL DERIVATIVES MODULATE CHEMOKINE RECEPTORS | AstraZeneca AB (SE) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002074763-A1 | BENZIMIDAZOL DERIVATIVES MODULATE CHEMOKINE RECEPTORS | ASTRAZENECA AB (SE) | 2002-09-26 | — | — | WO | disclosed |