Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14004120 | 0.90 | KIF11 (0.50) | KIF11 | |
| SCHEMBL22612073 | 0.86 | KIF11 (0.65) | KIF11 | |
| SCHEMBL22612075 | 0.86 | KIF11 (0.65) | KIF11 | |
| SCHEMBL22612072 | 0.86 | KIF11 (0.65) | KIF11 | |
| SCHEMBL10298221 | 0.86 | KIF11 (0.65) | KIF11 | |
| SCHEMBL4804833 | 0.86 | KIF11 (0.50) | KIF11 | |
| SCHEMBL4530986 | 0.86 | KIF11 (0.50) | KIF11 | |
| SCHEMBL4022115 | 0.84 | KIF11 (0.67) | KIF11 | |
| SCHEMBL4531442 | 0.84 | KIF11 (0.52) | KIF11 | |
| SCHEMBL10298222 | 0.83 | KIF11 (0.61) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080274052-A1 | RADIOFLORINATION METHODS | GE HEALTHCARE LIMITED (GB) | 2008-11-06 | — | — | US | disclosed |
| US-20080274052-A1 | RADIOFLORINATION METHODS | GE HEALTHCARE LIMITED (GB) | 2008-11-06 | — | — | US | disclosed |
| US-20080274052-A1 | RADIOFLORINATION METHODS | GE HEALTHCARE LIMITED (GB) | 2008-11-06 | — | — | US | disclosed |
| US-7368474-B2 | Radiofluorination methods | GE HEALTHCARE LIMITED (GB) | 2008-05-06 | — | — | US | disclosed |
| US-7368474-B2 | Radiofluorination methods | GE HEALTHCARE LIMITED (GB) | 2008-05-06 | — | — | US | disclosed |
| US-7368474-B2 | Radiofluorination methods | GE HEALTHCARE LIMITED (GB) | 2008-05-06 | — | — | US | disclosed |
| EP-1487762-B1 | RADIOFLUORINATION METHODS | GE HEALTHCARE LTD (GB) | 2007-02-28 | — | — | EP | disclosed |
| EP-1487762-B1 | RADIOFLUORINATION METHODS | GE HEALTHCARE LTD (GB) | 2007-02-28 | — | — | EP | disclosed |
| US-20050142061-A1 | Radiofluorination methods | GE HEALTHCARE LIMITED (GB) | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050142061-A1 | Radiofluorination methods | SSTR4, VIP, SSTR5 | KIF11 1686/4885 |
| US-20080274052-A1 | RADIOFLORINATION METHODS | VIP, QRFPR, SSTR4 | KIF11 2339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.