SCHEMBL4022115

SCHEMBL4022115

NCCOCCSC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10298221 0.98 KIF11 (0.65) KIF11
SCHEMBL22612075 0.98 KIF11 (0.65) KIF11
SCHEMBL22612072 0.98 KIF11 (0.65) KIF11
SCHEMBL22612073 0.98 KIF11 (0.65) KIF11
SCHEMBL10298222 0.88 KIF11 (0.61) KIF11
SCHEMBL4807284 0.84 KIF11 (0.55) KIF11
SCHEMBL4531442 0.82 KIF11 (0.52) KIF11
SCHEMBL10037243 0.81 KIF11 (0.64) KIF11
SCHEMBL4530986 0.81 KIF11 (0.50) KIF11
SCHEMBL4804833 0.81 KIF11 (0.50) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879906-A4 REVERSIBLE NUCLEOTIDE TERMINATORS AND USES THEREOF ADVANCED GENETIC ANALYSIS CORP (US) 2009-07-22 EP disclosed
EP-1879906-A2 REVERSIBLE NUCLEOTIDE TERMINATORS AND USES THEREOF AB Advanced Genetic Analysis Corporation (US) 2008-01-23 EP disclosed
WO-2006074351-A2 REVERSIBLE NUCLEOTIDE TERMINATORS AND USES THEREOF AGENCOURT PERSONAL GENOMICS (US) 2006-07-13 WO disclosed