Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.46 |
| ▸ | PPARA | Q07869 | 13/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4807971 | 1.00 | PPARG (0.46) | PPARGPPARAADRB3FFAR1PTPN1 | |
| SCHEMBL4818984 | 0.92 | ADRB3 (0.42) | PPARGPPARAADRB3FFAR1 | |
| SCHEMBL4818979 | 0.92 | ADRB3 (0.42) | PPARGPPARAADRB3FFAR1 | |
| SCHEMBL4808561 | 0.90 | PPARG (0.43) | PPARGPPARAADRB3 | |
| SCHEMBL4808571 | 0.90 | PPARG (0.43) | PPARGPPARAADRB3 | |
| SCHEMBL5699460 | 0.89 | FFAR1 (0.47) | PPARGPPARAADRB3FFAR1 | |
| SCHEMBL5699461 | 0.89 | FFAR1 (0.47) | PPARGPPARAADRB3FFAR1 | |
| SCHEMBL5699447 | 0.88 | KEAP1 (0.39) | ADRB3FFAR1 | |
| SCHEMBL5699440 | 0.88 | KEAP1 (0.39) | ADRB3FFAR1 | |
| SCHEMBL4817838 | 0.87 | ADRB3 (0.43) | PPARGPPARAADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417169-B2 | Amino alcohol derivatives, medicinal composition containing the same, and use of these | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2008-08-26 | — | — | US | disclosed |