Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5699440 | 1.00 | KEAP1 (0.39) | KEAP1NFE2L2FFAR1ADRB3ADRB1 | |
| SCHEMBL5699461 | 0.92 | FFAR1 (0.47) | FFAR1ADRB3 | |
| SCHEMBL5699460 | 0.92 | FFAR1 (0.47) | FFAR1ADRB3 | |
| SCHEMBL4818979 | 0.90 | ADRB3 (0.42) | FFAR1ADRB3 | |
| SCHEMBL4818984 | 0.90 | ADRB3 (0.42) | FFAR1ADRB3 | |
| SCHEMBL4816225 | 0.90 | ADRB3 (0.40) | FFAR1ADRB3 | |
| SCHEMBL4816218 | 0.90 | ADRB3 (0.40) | FFAR1ADRB3 | |
| SCHEMBL4820449 | 0.89 | ADRB3 (0.39) | FFAR1ADRB3ADRB1 | |
| SCHEMBL4820454 | 0.89 | ADRB3 (0.39) | FFAR1ADRB3ADRB1 | |
| SCHEMBL4807971 | 0.88 | PPARG (0.46) | FFAR1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1679304-A1 | AMINO ALCOHOL DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USE OF THESE | Kissei Pharmaceutical Co., Ltd. (JP) | 2006-07-12 | — | — | EP | disclosed |