Phosphine

Phosphine

SCHEMBL480827

P.c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.92

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.92
CYP3A4 P08684 1/20 0.92
ESR1 P03372 4/20 0.63
ESR2 Q92731 4/20 0.63
KDM4E B2RXH2 1/20 0.48
GAA P10253 1/20 0.48
ALDH1A1 P00352 4/20 0.38
NPSR1 Q6W5P4 1/20 0.37
DRD1 P21728 2/20 0.35
TSHR P16473 4/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
LMNA P02545 2/20 0.33
CA12 O43570 1/20 0.33
GLA P06280 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA14 Q9ULX7 1/20 0.33
ALOX12 P18054 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL27888053 1.00 TDP1 (0.92) TDP1CYP3A4ESR1ESR2KDM4E
Bromide SCHEMBL28010860 0.96 TDP1 (0.86) TDP1CYP3A4ESR1ESR2KDM4E
Hydrochloric Acid SCHEMBL27589494 0.96 TDP1 (0.86) TDP1CYP3A4ESR1ESR2KDM4E
Phosphine SCHEMBL27437879 0.96 TDP1 (0.86) TDP1CYP3A4ESR1ESR2KDM4E
Phosphine SCHEMBL15147637 0.96 TDP1 (0.86) TDP1CYP3A4ESR1ESR2KDM4E
Bromide SCHEMBL28010861 0.96 TDP1 (0.86) TDP1CYP3A4ESR1ESR2KDM4E
Iodide SCHEMBL27997104 0.96 TDP1 (0.86) TDP1CYP3A4ESR1ESR2KDM4E
Hydrochloric Acid SCHEMBL27532575 0.96 TDP1 (0.86) TDP1CYP3A4ESR1ESR2KDM4E
Phosphine SCHEMBL28252299 0.96 TDP1 (0.86) TDP1CYP3A4ESR1ESR2KDM4E
SCHEMBL5028587 0.96 TDP1 (1.00) TDP1CYP3A4ESR1ESR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111440295-B Polyester resin for boiling-resistant high-leveling powder coating and preparation method and application thereof 广东工业大学 2023-04-18 CN claimed
CN-111440295-A Polyester resin for boiling-resistant high-leveling powder coating and preparation method and application thereof 广东工业大学 2020-07-24 CN claimed
CN-101864149-B Flame-retardant transparent high-toughness epoxy potting resin and preparation method thereof WEI WANG 2012-04-04 CN claimed
CN-101864149-A Flame-retardant transparent high-toughness epoxy sealing resin and preparation method thereof ENMI CUI 2010-10-20 CN claimed
CN-117659611-A Preparation method of epoxy molding compound for semiconductor packaging 衡所华威电子有限公司 2024-03-08 CN disclosed
CN-117062810-A A series of dicyclic substituted aromatic carboxylic acid compounds 正大天晴药业集团股份有限公司 2023-11-14 CN disclosed
EP-4180043-A1 RUTHENIUM COMPLEXES Universidad de Almeria (ES) 2023-05-17 EP disclosed
CN-111440295-B Polyester resin for boiling-resistant high-leveling powder coating and preparation method and application thereof 广东工业大学 2023-04-18 CN disclosed
CN-111440295-B Polyester resin for boiling-resistant high-leveling powder coating and preparation method and application thereof 广东工业大学 2023-04-18 CN disclosed
WO-2023048016-A1 RESIN COMPOSITION, LIGHT-SHIELDING FILM, AND SUBSTRATE WITH PARTITIONING WALL 東レ株式会社 2023-03-30 WO disclosed
CN-113214319-B Quaternary phosphonium salt flame retardant and synthetic method and application thereof 上海交通大学 2022-06-14 CN disclosed
CN-111440295-A Polyester resin for boiling-resistant high-leveling powder coating and preparation method and application thereof 广东工业大学 2020-07-24 CN disclosed
CN-101218236-A 2-heterocyclyloxybenzoylamino heterocycles as glucokinase modulators for the treatment of type 2 diabetes ASTRAZENECA AB (SE) 2008-07-09 CN disclosed
CN-101094836-A Methods of making indazole compounds AGOURON PHARMA (US) 2007-12-26 CN disclosed
CN-101039904-A Is suitable for treating dopamine D3Heterocyclic compounds for receptor-modulated responsive disorders ABBOTT GMBH & CO KG (DE) 2007-09-19 CN disclosed
CN-1962802-A Semiconductor encapsulating epoxy resin composition and semiconductor device SHINETSU CHEMICAL CO (JP) 2007-05-16 CN disclosed
CN-1854185-A Semiconductor encapsulating epoxy resin composition and semiconductor device SHINETSU CHEMICAL CO (JP) 2006-11-01 CN disclosed
CN-1854186-A Semiconductor encapsulating epoxy resin composition and semiconductor device SHINETSU CHEMICAL CO (JP) 2006-11-01 CN disclosed
CN-1032243-C Reactivation of hydroformylation catalysts UNION CARBIDE CHEM PLASTIC (US) 1996-07-10 CN disclosed
CN-1066009-A The reactivation of carbonylation reaction catalyst UNION CARBIDE CHEM PLASTIC (US) 1992-11-11 CN disclosed