Sugi Predict

Sugi Predict / Compounds / SCHEMBL480834

SCHEMBL480834

SCHEMBL480834

CC(C)[C@@H](C)CC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GPBAR1 Q8TDU6 7/20 0.72
▸ EPHA2 P29317 4/20 0.72
▸ CASP7 P55210 3/20 0.72
▸ HIF1A Q16665 3/20 0.72
▸ TP53 P04637 2/20 0.72
▸ MAPK1 P28482 2/20 0.72
▸ HSD17B10 Q99714 2/20 0.72
▸ BLM P54132 2/20 0.72
▸ TDP1 Q9NUW8 2/20 0.72
▸ VDR P11473 2/20 0.72
▸ USP2 O75604 2/20 0.72
▸ LMNA P02545 2/20 0.72
▸ CYP3A4 P08684 2/20 0.72
▸ MDM4 O15151 1/20 0.72
▸ MAPT P10636 1/20 0.72
▸ HSPD1 P10809 1/20 0.72
▸ TSHR P16473 1/20 0.72
▸ PTPN2 P17706 1/20 0.72
▸ PTPN1 P18031 1/20 0.72
▸ BRCA1 P38398 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13988148 1.00 GPBAR1 (0.72) GPBAR1EPHA2CASP7HIF1ATP53
SCHEMBL167154 1.00 GPBAR1 (0.72) GPBAR1EPHA2CASP7HIF1ATP53
SCHEMBL14438447 1.00 GPBAR1 (0.72) GPBAR1EPHA2CASP7HIF1ATP53
SCHEMBL14116859 1.00 GPBAR1 (0.72) GPBAR1EPHA2CASP7HIF1ATP53
SCHEMBL14612012 1.00 GPBAR1 (0.72) GPBAR1EPHA2CASP7HIF1ATP53
SCHEMBL24710359 1.00 GPBAR1 (0.72) GPBAR1EPHA2CASP7HIF1ATP53
SCHEMBL14350523 1.00 GPBAR1 (0.72) GPBAR1EPHA2CASP7HIF1ATP53
SCHEMBL21748184 1.00 GPBAR1 (0.72) GPBAR1EPHA2CASP7HIF1ATP53
SCHEMBL21524957 1.00 GPBAR1 (0.72) GPBAR1EPHA2CASP7HIF1ATP53
SCHEMBL15346202 1.00 GPBAR1 (0.72) GPBAR1EPHA2CASP7HIF1ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 560 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410758-B1 — — None — — US claimed
US-20240301138-A1 POLMERIC TRANSFECTION REAGENTS TO DELIVER NUCLEIC ACIDS FOR HOST CELL MODIFICATION RJH BIOSCIENCES INC. (CA) 2024-09-12 — — US claimed
CN-113583077-B Process for preparing sterols 宜宾五粮液股份有限公司 2022-09-16 — — CN claimed
WO-2022150921-A1 POLYMERIC TRANSFECTION REAGENTS TO DELIVER NUCLEIC ACIDS FOR HOST CELL MODIFICATION RJH BIOSCIENCES INC. (CA) 2022-07-21 — — WO claimed
CN-113583077-A Process for preparing sterols 宜宾五粮液股份有限公司 2021-11-02 — — CN claimed
CN-111995653-A Preparation method of phytosterol/stanol ferulic acid ester 江苏大学 2020-11-27 — — CN claimed
US-20180296490-A1 BIOACTIVE DELIVERY VEHICLES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-10-18 — — US claimed
EP-2226066-B1 WATER-CONTAINING COMPOSITION COMPRISING A SOLUBILISED TRIAZINE SHISEIDO CO LTD (JP) 2016-05-04 — — EP claimed
EP-2545065-B1 WATER-SOLUBLE PHYTOSTEROL DERIVATIVES FOR REDUCING CHOLESTEROL AND PREPARATION THEREOF KIP BIOTECH LLC (US) 2015-11-11 — — EP claimed
CN-104277919-A Method for preparing solid lipid by combination of oryzanol and phytosterin UNIV HENAN TECHNOLOGY 2015-01-14 — — CN claimed
WO-2003105611-A2 BEVERAGES CONTAINING PLANT STEROLS THE COCA-COLA COMPANY (US) 2003-12-24 — — WO claimed
US-20030232118-A1 Beverages containing plant sterols THE COCA-COLA COMPANY 2003-12-18 — — US claimed
US-20020132804-A1 Preparation of sterol and stanol-esters RODEN ALLAN (US) 2002-09-19 — — US claimed
US-6410758-B2 ESTERIFICTAION USING FATTY ACID; FOOD GRADE; SOLVENT-FREE; NONCATALYTIC REACTION MCNEIL-PPC, INC. 2002-06-25 — — US claimed
EP-0925293-A4 METHOD OF PRODUCING AN EXTRUDED NUTRITIONAL SUPPLEMENT PRODUCT HENKEL CORP (US) 2002-04-17 — — EP claimed
US-20020010349-A1 PREPARATION OF STEROL AND STANOL-ESTERS MCNEIL-PPC, INC. 2002-01-24 — — US claimed
EP-1067135-A2 Preparation of sterol and stanol-esters McNEIL-PPC, INC. (US) 2001-01-10 — — EP claimed
US-6139872-A HEATING, EXTRUSION, COOLING, COMMINUTING PLASTIC NUTRITIONAL SUPPLEMENT HENKEL CORPORATION (US) 2000-10-31 — — US claimed
EP-0925293-A1 METHOD OF PRODUCING AN EXTRUDED NUTRITIONAL SUPPLEMENT PRODUCT HENKEL CORPORATION (US) 1999-06-30 — — EP claimed
WO-1998006714-A1 METHOD OF PRODUCING AN EXTRUDED NUTRITIONAL SUPPLEMENT PRODUCT HENKEL CORPORATION (US) 1998-02-19 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020010349-A1 PREPARATION OF STEROL AND STANOL-ESTERS CYP46A1, SREBF2, SREBF1 GPBAR1 380/4885EPHA2 507/4885CASP7 2952/4885
US-20020132804-A1 Preparation of sterol and stanol-esters CYP46A1, SREBF2, SREBF1 GPBAR1 380/4885EPHA2 507/4885CASP7 2952/4885
US-20240301138-A1 POLMERIC TRANSFECTION REAGENTS TO DELIVER NUCLEIC ACIDS FOR HOST CELL MODIFICATION POLRMT, POLM, PLTP GPBAR1 1564/4885EPHA2 2213/4885CASP7 2177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.