Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.50 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.50 |
| ▸ | SLC22A12 | Q96S37 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4806005 | 0.86 | SMN1; SMN2 (0.48) | HTTALOX15SLC22A12MAPTKDM4E | |
| SCHEMBL28059755 | 0.86 | PTK2 (0.55) | HTTALOX15FGFR1PTK2SLC22A12 | |
| SCHEMBL28541218 | 0.85 | SLC22A12 (0.49) | SLC22A12PARP1MTNR1APOLB | |
| SCHEMBL8223882 | 0.84 | CDC7 (0.42) | HTTALOX15PTK2SLC22A12MAPT | |
| Hydrochloric Acid SCHEMBL4869261 | 0.83 | CDC7 (0.41) | HTTALOX15PTK2SLC22A12MAPT | |
| SCHEMBL4856654 | 0.82 | PARP1 (0.55) | SLC22A12PARP1MTNR1A | |
| SCHEMBL4809049 | 0.81 | ALOX15 (0.52) | HTTALOX15FGFR1SLC22A12MAPT | |
| SCHEMBL28059754 | 0.81 | SLC22A12 (0.46) | HTTSLC22A12MAPTLMNASMN1; SMN2 | |
| SCHEMBL21310761 | 0.81 | ALOX15 (0.51) | HTTALOX15SLC22A12KDM4ELMNA | |
| SCHEMBL6491682 | 0.79 | ALOX15 (0.52) | HTTALOX15SLC22A12MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461681-B | Iridium-catalyzed N-phenyl-7 azaindole derivative and preparation method thereof | 陕西科技大学 | 2024-03-15 | — | — | CN | claimed |
| CN-113461681-A | Iridium-catalyzed N-phenyl-7 azaindole derivative and preparation method thereof | 陕西科技大学 | 2021-10-01 | — | — | CN | claimed |
| CN-113461681-B | Iridium-catalyzed N-phenyl-7 azaindole derivative and preparation method thereof | 陕西科技大学 | 2024-03-15 | — | — | CN | disclosed |
| CN-113461681-A | Iridium-catalyzed N-phenyl-7 azaindole derivative and preparation method thereof | 陕西科技大学 | 2021-10-01 | — | — | CN | disclosed |
| CN-104311553-B | Ortho position monochloro substituted compound and the synthetic method thereof of N-aryl azaindole | SHANGHAI UNIVERSITY (CN) | 2016-05-25 | — | — | CN | disclosed |
| US-20080090834-A1 | SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS | PFIZER INC | 2008-04-17 | — | — | US | disclosed |
| US-20080090834-A1 | SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS | PFIZER INC | 2008-04-17 | — | — | US | disclosed |
| US-20080090834-A1 | SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS | PFIZER INC | 2008-04-17 | — | — | US | disclosed |
| WO-2008004117-A1 | SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2008-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090834-A1 | SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS | PDE5A, PDE3B, PDE12 | HTT 2529/4885ALOX15 2543/4885FGFR1 3153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.