Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 10/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28541218 | 0.85 | SLC22A12 (0.49) | SLC22A12PARP1POLBMEN1PABPC1 | |
| SCHEMBL4806005 | 0.83 | SMN1; SMN2 (0.48) | SLC22A12POLBMEN1PABPC1KMT2A | |
| SCHEMBL4856654 | 0.82 | PARP1 (0.55) | SLC22A12PARP1MTNR1ACDC7CDK2 | |
| SCHEMBL4809547 | 0.81 | HTT (0.51) | SLC22A12PARP1POLBMTNR1AALDH1A1 | |
| SCHEMBL4807511 | 0.80 | IDO1 (0.46) | SLC22A12PARP1RAB9A | |
| SCHEMBL4878241 | 0.79 | IDO1 (0.44) | SLC22A12PARP1MTNR1ACDC7CDK2 | |
| SCHEMBL4872731 | 0.78 | SLC22A12 (0.39) | SLC22A12PARP1POLBMEN1KMT2A | |
| SCHEMBL28537449 | 0.76 | L3MBTL1 (0.54) | SLC22A12PARP1MTNR1ACDC7CDK2 | |
| SCHEMBL2295195 | 0.76 | CDC7 (0.53) | SLC22A12PARP1POLBMTNR1ACDC7 | |
| SCHEMBL8223882 | 0.76 | CDC7 (0.42) | SLC22A12PARP1POLBMTNR1ACDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104311553-B | Ortho position monochloro substituted compound and the synthetic method thereof of N-aryl azaindole | SHANGHAI UNIVERSITY (CN) | 2016-05-25 | — | — | CN | disclosed |