Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2563747 | 0.91 | RXFP1 (0.38) | GAACASRRXFP1SMN1; SMN2NPC1 | |
| SCHEMBL2563743 | 0.91 | RXFP1 (0.38) | GAACASRRXFP1SMN1; SMN2NPC1 | |
| SCHEMBL2120498 | 0.87 | SENP1 (0.41) | GAACASRRXFP1SMN1; SMN2NPC1 | |
| SCHEMBL3151999 | 0.85 | ALDH1A1 (0.40) | GAARXFP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3152005 | 0.85 | ALDH1A1 (0.40) | GAARXFP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL480533 | 0.84 | ALDH1A1 (0.41) | GAARXFP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL480535 | 0.84 | ALDH1A1 (0.41) | GAARXFP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL480521 | 0.84 | CASR (0.41) | CASRSMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL480523 | 0.84 | CASR (0.41) | CASRSMN1; SMN2NPC1RAB9AMAPK1 | |
| SCHEMBL480455 | 0.83 | SMN1; SMN2 (0.41) | GAACASRRXFP1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |