Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4810851 | 0.83 | MITF (0.36) | ELANEHPGDKDM4EMEN1PLK4 | |
| SCHEMBL11741672 | 0.81 | KDM4E (0.35) | HPGDKDM4EMEN1PLK4IKBKB | |
| SCHEMBL9184302 | 0.72 | MAPT (0.39) | HPGDKDM4EMEN1PLK4IKBKB | |
| SCHEMBL15120704 | 0.69 | MCL1 (0.37) | ELANEHPGDKDM4EMEN1PLK4 | |
| SCHEMBL5381715 | 0.67 | ALDH2 (0.42) | HPGDKDM4EMEN1PLK4IKBKB | |
| SCHEMBL8418907 | 0.67 | MAPT (0.40) | ELANEHPGDKDM4EMEN1PLK4 | |
| SCHEMBL15763 | 0.67 | CYP1A2 (0.43) | ELANEHPGDKDM4EMEN1PLK4 | |
| SCHEMBL1513280 | 0.66 | ESR2 (0.39) | HPGDKDM4EMEN1PLK4IKBKB | |
| SCHEMBL17456072 | 0.64 | CYP1A2 (0.42) | ELANEHPGDKDM4EMEN1PLK4 | |
| SCHEMBL25994740 | 0.64 | CYP1A2 (0.42) | ELANEHPGDKDM4EMEN1PLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7444050-B2 | S-shaped curved optical waveguide and optical device | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2008-10-28 | — | — | US | disclosed |
| US-20070036501-A1 | S-shaped curved optical waveguide and optical device | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2007-02-15 | — | — | US | disclosed |