SCHEMBL8418907

SCHEMBL8418907

O=c1oc(=O)c2c(Cl)c3c(=O)oc(=O)c3cc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.40
BLM P54132 3/20 0.40
LMNA P02545 3/20 0.40
TP53 P04637 2/20 0.40
POLB P06746 2/20 0.40
CYP2C9 P11712 2/20 0.40
ALOX15 P16050 2/20 0.40
CYP2C19 P33261 2/20 0.40
HSD17B10 Q99714 2/20 0.40
ALDH1A1 P00352 2/20 0.40
CYP1A2 P05177 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
GMNN O75496 1/20 0.40
ELANE P08246 1/20 0.40
CTSG P08311 1/20 0.40
CTSA P10619 1/20 0.40
CYP2D6 P10635 1/20 0.40
NFKB1 P19838 1/20 0.40
THPO P40225 1/20 0.40
MTOR P42345 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11880818 0.82 MAPT (0.44) MAPTBLMLMNATP53POLB
SCHEMBL4276659 0.78 LMNA (0.42) MAPTBLMLMNATP53POLB
SCHEMBL8180408 0.78 ALDH1A1 (0.33) MAPTBLMLMNATP53POLB
SCHEMBL6713095 0.76 LMNA (0.41) MAPTBLMLMNATP53POLB
SCHEMBL9184302 0.75 MAPT (0.39) MAPTBLMLMNATP53POLB
SCHEMBL5381715 0.75 ALDH2 (0.42) MAPTBLMLMNATP53POLB
SCHEMBL15763 0.74 CYP1A2 (0.43) MAPTBLMLMNATP53POLB
SCHEMBL3895699 0.72 ALDH1A1 (0.33) MAPTBLMLMNATP53POLB
SCHEMBL17456072 0.72 CYP1A2 (0.42) MAPTBLMLMNATP53POLB
SCHEMBL25994740 0.72 CYP1A2 (0.42) MAPTBLMLMNATP53POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5876891-A POLYIMIDE FROM AN AROMATIC POLYCHALCOGEN DIAMINE SUCH AS POLYPHENYLENE THIOETHER DIAMINE AND AN AROMATIC DIANHYDRIDE, PHTHALOCYANINE OR PERYLENE PIGMENTS MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1999-03-02 US disclosed
US-5654367-A ALTERNATING POLYIMIDE OR POLYAMIDEIMIDE COPOLYMER USEFUL AS PHOTOSENSITIVE MATERIAL IN SPATIAL LIGHT MODULATOR MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1997-08-05 US disclosed
US-5597889-A POLYIMIDES MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1997-01-28 US disclosed
US-5486442-A Organic polymer and preparation and use in crystal spatial light modulator MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1996-01-23 US disclosed
EP-0449117-A2 Organic polymer and preparation and use thereof MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1991-10-02 EP disclosed