Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6812111 | 0.87 | CALM1 (0.51) | SLC18A2 | |
| SCHEMBL6967476 | 0.86 | HRH3 (0.43) | SLC18A2 | |
| SCHEMBL13393801 | 0.83 | HRH3 (0.46) | — | |
| SCHEMBL19681498 | 0.82 | MAOB (0.60) | SLC18A2 | |
| SCHEMBL4819501 | 0.81 | TAAR1 (0.53) | — | |
| SCHEMBL6811867 | 0.81 | CALM1 (0.54) | — | |
| SCHEMBL6967480 | 0.81 | HRH3 (0.41) | SLC18A2 | |
| SCHEMBL4820798 | 0.80 | — | — | |
| SCHEMBL6808824 | 0.78 | SLC18A2 (0.45) | SLC18A2 | |
| SCHEMBL16838790 | 0.78 | MAOB (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040266824-A1 | 2,6-disubstituted piperidines and piperazine compounds | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2004-12-30 | — | — | US | claimed |
| US-7368443-B2 | 2,6-disubstituted piperidines and piperazine compounds | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2008-05-06 | — | — | US | disclosed |
| US-20040266824-A1 | 2,6-disubstituted piperidines and piperazine compounds | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266824-A1 | 2,6-disubstituted piperidines and piperazine compounds | GRM5, GRM6, SLC1A2 | SLC18A2 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.