Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4810155 | 0.86 | SLC18A2 (0.50) | SLC18A2 | |
| SCHEMBL6973609 | 0.83 | ALDH1A1 (0.49) | HRH3 | |
| SCHEMBL6981221 | 0.80 | POLB (0.45) | — | |
| SCHEMBL6967480 | 0.77 | HRH3 (0.41) | HRH3SLC18A2HTTMAOB | |
| SCHEMBL6976836 | 0.77 | GAA (0.40) | HRH3 | |
| SCHEMBL13393801 | 0.77 | HRH3 (0.46) | HRH3MAOB | |
| SCHEMBL6812111 | 0.75 | CALM1 (0.51) | SLC18A2 | |
| SCHEMBL19681498 | 0.73 | MAOB (0.60) | HRH3SLC18A2HTTMAOB | |
| SCHEMBL16838790 | 0.72 | MAOB (0.63) | HRH3MAOB | |
| SCHEMBL6978953 | 0.72 | NR1H4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |