Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.76 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15292027 | 1.00 | CYP19A1 (0.76) | CYP19A1DDB1CRBNCES1GRIN2B | |
| SCHEMBL20585273 | 1.00 | CYP19A1 (0.76) | CYP19A1DDB1CRBNCES1GRIN2B | |
| SCHEMBL15874625 | 1.00 | CYP19A1 (0.76) | CYP19A1DDB1CRBNCES1GRIN2B | |
| SCHEMBL9149653 | 0.89 | CYP19A1 (0.62) | CYP19A1DDB1CRBNCES1SIGMAR1 | |
| SCHEMBL13267868 | 0.86 | CYP19A1 (0.68) | CYP19A1SIGMAR1HTR2BMAPTDRD2 | |
| SCHEMBL9375189 | 0.86 | CYP19A1 (0.68) | CYP19A1SIGMAR1HTR1ALMNACYP1A2 | |
| SCHEMBL15874815 | 0.86 | CYP19A1 (0.68) | CYP19A1SIGMAR1HTR2BMAPTDRD2 | |
| SCHEMBL9148195 | 0.86 | CYP19A1 (1.00) | CYP19A1DDB1CRBNTP53MAPT | |
| SCHEMBL15875019 | 0.86 | CYP19A1 (0.68) | CYP19A1SIGMAR1HTR1ALMNACYP1A2 | |
| SCHEMBL19322772 | 0.84 | CYP19A1 (0.64) | CYP19A1CES1ACHETP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442800-B2 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | PROMERUS LLC (US) | 2008-10-28 | — | — | US | claimed |
| EP-1885669-A1 | NUCLEOPHILIC HETEROCYCLIC CARBENE DERIVATIVES OF PD(ACAC)2 FOR CROSS-COUPLING REACTIONS | Promerus LLC (US) | 2008-02-13 | — | — | EP | claimed |
| US-20060287544-A1 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | PROMERUS LLC (US) | 2006-12-21 | — | — | US | claimed |
| WO-2006128097-A1 | NUCLEOPHILIC HETEROCYCLIC CARBENE DERIVATIVES OF PD(ACAC)2 FOR CROSS-COUPLING REACTIONS | PROMERUS LLC (US) | 2006-11-30 | — | — | WO | claimed |
| EP-0346226-B1 | PROCESS FOR THE PREPARATION OF 4-ARYL DISUBSTITUTED-1-TETRALONES | SYNTHELABO (FR) | 1993-02-17 | — | — | EP | claimed |
| EP-4276188-A1 | METHOD FOR SYNTHESIZING CHIRAL AMINE COMPOUND | Asymchem Laboratories (Tianjin) Co., Ltd. (CN) | 2023-11-15 | — | — | EP | disclosed |
| EP-4273237-A1 | TRANSAMINASE MUTANT AND APPLICATION THEREOF | Asymchem Laboratories (Tianjin) Co., Ltd. (CN) | 2023-11-08 | — | — | EP | disclosed |
| EP-3551639-B1 | NOVEL CHIRAL DIHYDROBENZOAZAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2023-08-23 | — | — | EP | disclosed |
| EP-3551639-B1 | NOVEL CHIRAL DIHYDROBENZOAZAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2023-08-23 | — | — | EP | disclosed |
| CN-113527130-B | Synthesis method of alpha-amide, alpha-aryl quaternary carboketone compound | 兰州大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-113527130-A | Synthetic method of alpha-amide and alpha-aryl quaternary carbon ketone compound | 兰州大学 | 2021-10-22 | — | — | CN | disclosed |
| CN-111233599-B | Aromatic ring ortho-iodoalkanone and synthetic method and application thereof | 兰州大学 | 2021-07-20 | — | — | CN | disclosed |
| EP-0583346-A1 | BICYCLIC AMIDES AS INHIBITORS OF ACYL-COENZYME A: CHOLESTEROL ACYL TRANSFERASE | SCHERING CORPORATION (US) | 1994-02-23 | — | — | EP | disclosed |
| EP-0267734-B1 | Chemical compounds | ZENECA LTD (GB) | 1994-01-26 | — | — | EP | disclosed |
| WO-1992018462-A1 | BICYCLIC AMIDES AS INHIBITORS OF ACYL-COENZYME A: CHOLESTEROL ACYL TRANSFERASE | SCHERING CORPORATION (US) | 1992-10-29 | — | — | WO | disclosed |
| US-5041610-A | Resorcyclic acid lactone derivatives as animal growth promotants | INTERNATIONAL MINERALS & CHEMICAL CORP. (US) | 1991-08-20 | — | — | US | disclosed |
| US-5019655-A | Method of preparing 4-dichlorophenyl-1-tetralones | DELALANDE S.A. (FR) | 1991-05-28 | — | — | US | disclosed |
| US-5019655-A | Method of preparing 4-dichlorophenyl-1-tetralones | DELALANDE S.A. (FR) | 1991-05-28 | — | — | US | disclosed |
| US-4877811-A | FUNGICIDES, INSECTICIDES, MITICIDES, PLANTH GROWTH REGULATORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-10-31 | — | — | US | disclosed |
| EP-0267734-A2 | Chemical compounds | ZENECA LIMITED (GB) | 1988-05-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287544-A1 | Nucleophilic heterocyclic carbene derivatives of Pd(acac)2 for cross-coupling reactions | NDC1, DDC, PDCD1LG2 | CYP19A1 1884/4885DDB1 754/4885CRBN 3187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.