SCHEMBL4811219

SCHEMBL4811219

Cc1ccc(N(C([NH])=O)c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 2/20 0.53
NPSR1 Q6W5P4 2/20 0.50
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
KMT2A Q03164 4/20 0.43
ALDH1A1 P00352 4/20 0.43
MEN1 O00255 3/20 0.43
GAA P10253 1/20 0.43
PTGIR P43119 2/20 0.43
PTGDR Q13258 1/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
POLB P06746 2/20 0.42
HTT P42858 1/20 0.42
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1386191 0.87 NPSR1 (0.64) TRPM8NPSR1KMT2AALDH1A1MEN1
SCHEMBL2091758 0.83 TRPM8 (0.56) TRPM8NPSR1CES2CES1KMT2A
SCHEMBL2091757 0.82 TRPM8 (0.54) TRPM8NPSR1CES2CES1KMT2A
SCHEMBL5932654 0.80 TRPM8 (0.53) TRPM8NPSR1CES2CES1KMT2A
SCHEMBL1118866 0.80 TRPM8 (0.53) TRPM8NPSR1CES2CES1KMT2A
SCHEMBL77003 0.80 TRPM8 (0.53) TRPM8NPSR1CES2CES1KMT2A
SCHEMBL5932651 0.80 TRPM8 (0.53) TRPM8NPSR1CES2CES1KMT2A
SCHEMBL77001 0.80 TRPM8 (0.53) TRPM8NPSR1CES2CES1KMT2A
SCHEMBL31393773 0.78 NR3C2 (0.59) TRPM8NPSR1CES2CES1KMT2A
SCHEMBL2490876 0.78 TRPM8 (0.51) TRPM8NPSR1CES2CES1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7455959-B2 Photographic element containing a speed-enhancing compound EASTMAN KODAK COMPANY (US) 2008-11-25 US disclosed
US-20080248433-A1 PHOTOGRAPHIC ELEMENT CONTAINING A SPEED-ENHANCING COMPOUND NPEC INC. 2008-10-09 US disclosed
US-7354701-B2 Photographic element with speed-enhancing compound EASTMAN KODAK COMPANY (US) 2008-04-08 US disclosed
US-20070128560-A1 Photographic element with speed-enhancing compound EASTMAN KODAK COMPANY 2007-06-07 US disclosed
US-6887656-B2 Color photographic element containing improved heterocyclic speed enhancing compound EASTMAN KODAK COMPANY (US) 2005-05-03 US disclosed
WO-2005036263-A2 PHOTOGRAPHIC ELEMENT WITH SPEED-ENHANCING COMPOUND EASTMAN KODAK COMPANY (US) 2005-04-21 WO disclosed
US-20040142289-A1 COLOR PHOTOGRAPHIC ELEMENT CONTAINING IMPROVED HETEROCYCLIC SPEED ENHANCING COMPOUND EASTMAN KODAK COMPANY 2004-07-22 US disclosed
EP-1439416-A1 Color photographic element containing improved heterocyclic speed enhancing compound EASTMAN KODAK COMPANY (US) 2004-07-21 EP disclosed