SCHEMBL77003

SCHEMBL77003

Cc1ccc(N(C(N)=O)c2ccccc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 2/20 0.53
NPSR1 Q6W5P4 2/20 0.50
ALDH1A1 P00352 5/20 0.47
CES2 O00748 1/20 0.45
CES1 P23141 1/20 0.45
KMT2A Q03164 4/20 0.43
MEN1 O00255 3/20 0.43
LMNA P02545 1/20 0.43
GAA P10253 1/20 0.43
PTGIR P43119 1/20 0.43
PTGDR Q13258 1/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
POLB P06746 1/20 0.42
HTT P42858 1/20 0.42
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
ALOX5 P09917 1/20 0.42
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL77001 1.00 TRPM8 (0.53) TRPM8NPSR1ALDH1A1CES2CES1
SCHEMBL1954828 0.92 ALOX5 (0.47) TRPM8NPSR1ALDH1A1CES2CES1
Methyl Alcohol SCHEMBL28147253 0.87 NPSR1 (0.58) TRPM8NPSR1ALDH1A1KMT2AMEN1
SCHEMBL75885 0.87 NPSR1 (0.64) TRPM8NPSR1ALDH1A1KMT2AMEN1
SCHEMBL28148401 0.87 NPSR1 (0.64) TRPM8NPSR1ALDH1A1KMT2AMEN1
SCHEMBL75883 0.87 NPSR1 (0.64) TRPM8NPSR1ALDH1A1KMT2AMEN1
Acetic Acid SCHEMBL28331100 0.85 NPSR1 (0.56) TRPM8NPSR1ALDH1A1KMT2AMEN1
Urea SCHEMBL23005263 0.85 NPSR1 (0.61) TRPM8NPSR1ALDH1A1KMT2AMEN1
SCHEMBL28023499 0.85 NPSR1 (0.61) TRPM8NPSR1ALDH1A1KMT2AMEN1
Hydrogen Sulfide SCHEMBL28272945 0.85 NPSR1 (0.61) TRPM8NPSR1ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2243177-B1 PHOSPHORESCENT OLED HAVING DOUBLE HOLE-BLOCKING LAYERS GLOBAL OLED TECHNOLOGY LLC (US) 2019-05-15 EP disclosed
EP-1911069-B1 LOW VOLTAGE ORGANIC ELECTROLUMINESCENT ELEMENT GLOBAL OLED TECHNOLOGY LLC (US) 2018-08-22 EP disclosed
EP-2396801-B1 OLED DEVICE WITH FLUORANTHENE-MACROCYCLIC MATERIALS GLOBAL OLED TECHNOLOGY LLC (US) 2018-05-23 EP disclosed
US-9666826-B2 Electroluminescent device including an anthracene derivative GLOBAL OLED TECHNOLOGY LLC (US) 2017-05-30 US disclosed
US-9634256-B2 Electroluminescent devices including organic EIL layer GLOBAL OLED TECHNOLOGY LLC (US) 2017-04-25 US disclosed
US-9620721-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2017-04-11 US disclosed
EP-2232612-B1 OLED DEVICE EMPLOYING ALKALI METAL CLUSTER COMPOUNDS GLOBAL OLED TECHNOLOGY LLC (US) 2017-02-08 EP disclosed
US-9523011-B2 Recirculating inkjet printing fluid EASTMAN KODAK COMPANY (US) 2016-12-20 US disclosed
EP-1920481-B1 ELECTROLUMINESCENT DEVICE WITH RED TRIPLET EMITTER GLOBAL OLED TECHNOLOGY LLC (US) 2016-10-12 EP disclosed
EP-1807482-B1 ORGANIC ELEMENT FOR ELECTROLUMINESCENT DEVICES GLOBAL OLED TECHNOLOGY LLC (US) 2016-06-08 EP disclosed
US-5340708-A Photographic elements containing new dye-forming tris couplers EASTMAN KODAK COMPANY (US) 1994-08-23 US disclosed
EP-0608958-A1 Photographic material and process comprising a thiol bleach assist in the low sensitivity layer of a triple coat EASTMAN KODAK COMPANY (US) 1994-08-03 EP disclosed
EP-0608957-A1 Photographic element and process employing a combination of yellow couplers EASTMAN KODAK COMPANY (US) 1994-08-03 EP disclosed
EP-0608956-A1 Photographic element and process having improved response to developer variations EASTMAN KODAK COMPANY (US) 1994-08-03 EP disclosed
EP-0603964-A2 Azopyrazolone masking couplers EASTMAN KODAK COMPANY (US) 1994-06-29 EP disclosed
US-5274104-A N-substituted heterocyclic derivatives useful in the treatment of cardiovascular disorders ELF SANOFI, A FRENCH CORP. (FR) 1993-12-28 US disclosed
US-5194660-A Processes for producing carbamates and isocyanates UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1993-03-16 US disclosed
EP-0083096-B1 PRODUCTION OF URETHANE COMPOUNDS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-02-25 EP disclosed
US-4621149-A PLATINUM GROUP METAL HALOGEN OR HALOGEN COMPOUND ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1986-11-04 US disclosed
EP-0083096-A2 Production of urethane compounds Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1983-07-06 EP disclosed