Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.69 |
| ▸ | TRPV1 | Q8NER1 | 19/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4809369 | 0.88 | TRPV1 (0.71) | TRPV4TRPV1 | |
| SCHEMBL4806055 | 0.86 | TRPV1 (0.61) | TRPV4TRPV1 | |
| SCHEMBL4815470 | 0.86 | TRPV4 (0.56) | TRPV4TRPV1 | |
| SCHEMBL4816141 | 0.86 | TRPV4 (0.66) | TRPV4TRPV1 | |
| SCHEMBL4808062 | 0.86 | TRPV1 (0.69) | TRPV4TRPV1 | |
| SCHEMBL3873320 | 0.85 | TRPV1 (0.78) | TRPV4TRPV1 | |
| SCHEMBL4816131 | 0.85 | TRPV1 (0.74) | TRPV4TRPV1 | |
| SCHEMBL14253432 | 0.84 | TRPV1 (0.67) | TRPV4TRPV1 | |
| SCHEMBL4815621 | 0.84 | TRPV1 (0.72) | TRPV1 | |
| SCHEMBL4811455 | 0.83 | TRPV1 (0.65) | TRPV4TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7338950-B2 | Amide compounds as ion channel ligands and uses thereof | RENOVIS, INC. (US) | 2008-03-04 | — | — | US | disclosed |
| US-7338950-B2 | Amide compounds as ion channel ligands and uses thereof | RENOVIS, INC. (US) | 2008-03-04 | — | — | US | disclosed |
| US-7338950-B2 | Amide compounds as ion channel ligands and uses thereof | RENOVIS, INC. (US) | 2008-03-04 | — | — | US | disclosed |