Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.66 |
| ▸ | TRPV1 | Q8NER1 | 17/20 | 0.64 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4808062 | 0.89 | TRPV1 (0.69) | TRPV4TRPV1GRM4 | |
| SCHEMBL4811455 | 0.87 | TRPV1 (0.65) | TRPV4TRPV1GRM4 | |
| SCHEMBL4811446 | 0.86 | TRPV4 (0.69) | TRPV4TRPV1 | |
| SCHEMBL4811324 | 0.85 | TRPV1 (0.68) | TRPV1 | |
| SCHEMBL4809369 | 0.85 | TRPV1 (0.71) | TRPV4TRPV1 | |
| SCHEMBL3873320 | 0.82 | TRPV1 (0.78) | TRPV4TRPV1TP53 | |
| SCHEMBL14083879 | 0.82 | TRPV1 (0.78) | TRPV4TRPV1 | |
| SCHEMBL4816131 | 0.82 | TRPV1 (0.74) | TRPV4TRPV1 | |
| SCHEMBL14253432 | 0.82 | TRPV1 (0.67) | TRPV4TRPV1 | |
| SCHEMBL3872091 | 0.80 | TRPV1 (0.78) | TRPV4TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7338950-B2 | Amide compounds as ion channel ligands and uses thereof | RENOVIS, INC. (US) | 2008-03-04 | — | — | US | disclosed |