⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974043 | 0.82 | — | — | |
| SCHEMBL275931 | 0.67 | — | — | |
| SCHEMBL1374641 | 0.67 | — | — | |
| SCHEMBL355337 | 0.67 | — | — | |
| SCHEMBL31955606 | 0.67 | MAPT (0.44) | — | |
| SCHEMBL124901 | 0.67 | — | — | |
| SCHEMBL9712110 | 0.67 | — | — | |
| SCHEMBL9613581 | 0.67 | — | — | |
| SCHEMBL215853 | 0.67 | — | — | |
| SCHEMBL678750 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112679328-B | Industrial production method of 3-trifluoromethyl-2-cyclohexene-1-one | 南京药石科技股份有限公司 | 2023-09-15 | — | — | CN | claimed |
| CN-112679328-A | Industrial production method of 3-trifluoromethyl-2-cyclohexene-1-ketone | 南京药石科技股份有限公司 | 2021-04-20 | — | — | CN | claimed |
| US-20240400501-A1 | 3,4-DISUBSTITUTED 3-CYCLOBUTENE-1,2-DIONES AND USE THEREOF | ALLERGAN, INC. | 2024-12-05 | — | — | US | disclosed |
| US-RE49934-E1 | Inhibitors of cellular metabolic processes | SERVIER PHARMACEUTICALS LLC (US) | 2024-04-23 | — | — | US | disclosed |
| CN-112679328-B | Industrial production method of 3-trifluoromethyl-2-cyclohexene-1-one | 南京药石科技股份有限公司 | 2023-09-15 | — | — | CN | disclosed |
| US-20220402866-A1 | 3,4-DISUBSTITUTED 3-CYCLOBUTENE-1,2-DIONES AND USE THEREOF | ALLERGAN, INC. | 2022-12-22 | — | — | US | disclosed |
| US-20220402866-A1 | 3,4-DISUBSTITUTED 3-CYCLOBUTENE-1,2-DIONES AND USE THEREOF | ALLERGAN, INC. | 2022-12-22 | — | — | US | disclosed |
| CN-109890822-B | Inhibitors of cellular metabolic processes | 安吉奥斯医药品有限公司 | 2022-08-30 | — | — | CN | disclosed |
| US-11325914-B1 | Inhibitors of cellular metabolic processes | SERVIER PHARMACEUTICALS LLC (US) | 2022-05-10 | — | — | US | disclosed |
| US-11325914-B1 | Inhibitors of cellular metabolic processes | SERVIER PHARMACEUTICALS LLC (US) | 2022-05-10 | — | — | US | disclosed |
| US-11208377-B2 | 3,4-disubstituted 3-cyclobutene-1,2-diones and use thereof | ALLERGAN, INC. (US) | 2021-12-28 | — | — | US | disclosed |
| US-7384580-B2 | Method of preparing organomagnesium compounds | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2008-06-10 | — | — | US | disclosed |
| US-7384580-B2 | Method of preparing organomagnesium compounds | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2008-06-10 | — | — | US | disclosed |
| US-20070194468-A1 | Method of preparing organomagnesium compounds | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2007-08-23 | — | — | US | disclosed |
| US-20070194468-A1 | Method of preparing organomagnesium compounds | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2007-08-23 | — | — | US | disclosed |
| US-20070194468-A1 | Method of preparing organomagnesium compounds | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2007-08-23 | — | — | US | disclosed |
| US-20050218532-A1 | Method of preparing organomagnesium compounds | LUDWIG-MAXIMILIANS-UNIVERSITAT MUNCHEN (DE) | 2005-10-06 | — | — | US | disclosed |
| EP-1582524-A1 | Method of preparing organomagnesium compounds | Ludwig Maximilians Universität (DE) | 2005-10-05 | — | — | EP | disclosed |
| EP-1582523-A1 | Method of preparing organomagnesium compounds | Ludwig-Maximilians-Universität München (DE) | 2005-10-05 | — | — | EP | disclosed |
| EP-0737329-B1 | TABULAR GRAIN EMULSIONS WITH SELECTED SITE HALIDE CONVERSIONS AND PROCESSES FOR THEIR PREPARATION | EASTMAN KODAK CO (US) | 2002-04-03 | — | — | EP | disclosed |