SCHEMBL215853

SCHEMBL215853

O=C1C=C(Cl)CCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13482126 0.94
SCHEMBL28756264 0.67 MT-CO2 (0.53)
SCHEMBL31955606 0.67 MAPT (0.44)
SCHEMBL9712110 0.67
SCHEMBL1374641 0.67
SCHEMBL124901 0.67
SCHEMBL355337 0.67
SCHEMBL4811550 0.67
SCHEMBL678750 0.67
SCHEMBL2600398 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0001556-B1 CYCLOHEXENONE DERIVATIVES, METHOD OF THEIR PREPARATION, HERBICIDAL COMPOSITION CONTAINING THEM AND USE OF SAID CYCLOHEXENONE DERIVATIVES AND HERBICIDAL COMPOSITION, RESPECTIVELY STAUFFER CHEMICAL COMPANY (US) 1981-06-17 EP claimed
EP-0001556-A2 Cyclohexenone derivatives, method of their preparation, herbicidal composition containing them and use of said cyclohexenone derivatives and herbicidal composition, respectively STAUFFER CHEMICAL COMPANY (US) 1979-05-02 EP claimed
US-20250268903-A1 RXFP1 AGONISTS BRISTOL MYERS SQUIBB CO (US) 2025-08-28 US disclosed
US-12371428-B2 Pyridone compounds and methods of use EXELIXIS, INC. (US) 2025-07-29 US disclosed
EP-4423058-A1 RXFP1 AGONISTS Bristol-Myers Squibb Company (US) 2024-09-04 EP disclosed
CN-118451058-A RXFP1 agonists 百时美施贵宝公司 2024-08-06 CN disclosed
WO-2023178061-A1 BIOCATALYTIC SYNTHESIS OF (1S,3S)-3-HYDROXYCYCLOHEXANE-1-CARBOXYLIC ACID COMPOUNDS BRISTOL-MYERS SQUIBB COMPANY (US) 2023-09-21 WO disclosed
WO-2023077040-A1 RXFP1 AGONISTS BRISTOL-MYERS SQUIBB COMPANY (US) 2023-05-04 WO disclosed
US-20220315579-A1 PYRIDONE COMPOUNDS AND METHODS OF USE EXELIXIS, INC. 2022-10-06 US disclosed
EP-4034532-A1 PYRIDONE COMPOUNDS AND METHODS OF USE IN THE MODULATION OF A PROTEIN KINASE Exelixis, Inc. (US) 2022-08-03 EP disclosed
CN-114787144-A Pyridone compounds and methods for modulating protein kinases 埃克塞里艾克西斯公司 2022-07-22 CN disclosed
US-4737442-A INCLUDING A SENSITIZER AND A BLOCKED DEVELOPMENT RESTRAINER; FREE OF BLACK SPOTS FUJI PHOTO FILM CO., LTD. (JP) 1988-04-12 US disclosed
US-4518685-A BLOCKED AGENT FOR STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1985-05-21 US disclosed
EP-0125523-A2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1984-11-21 EP disclosed
US-4336062-A Herbicidal cyclohexenone derivatives STAUFFER CHEMICAL COMPANY (US) 1982-06-22 US disclosed
EP-0001556-B1 CYCLOHEXENONE DERIVATIVES, METHOD OF THEIR PREPARATION, HERBICIDAL COMPOSITION CONTAINING THEM AND USE OF SAID CYCLOHEXENONE DERIVATIVES AND HERBICIDAL COMPOSITION, RESPECTIVELY STAUFFER CHEMICAL COMPANY (US) 1981-06-17 EP disclosed
EP-0001556-A2 Cyclohexenone derivatives, method of their preparation, herbicidal composition containing them and use of said cyclohexenone derivatives and herbicidal composition, respectively STAUFFER CHEMICAL COMPANY (US) 1979-05-02 EP disclosed
US-4053476-A 7-AZA-6-ALKOXY-1-TETRALONES G. D. SEARLE & CO. (US) 1977-10-11 US disclosed
US-4012391-A 11β-Alkyl-2-azaestratrienes and intermediates G. D. SEARLE & CO. (US) 1977-03-15 US disclosed
US-4007194-A Process and intermediates for manufacture of 2-azasterioids G. D. SEARLE & CO. (US) 1977-02-08 US disclosed