SCHEMBL678750

SCHEMBL678750

O=C1C=C(Br)CCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL867291 0.82
SCHEMBL5225774 0.67 HTR2C (0.37)
SCHEMBL355337 0.67
SCHEMBL4811550 0.67
SCHEMBL31955606 0.67 MAPT (0.44)
SCHEMBL9712110 0.67
SCHEMBL215853 0.67
SCHEMBL124901 0.67
SCHEMBL1374641 0.67
SCHEMBL2600398 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5618982-A SIMPLE INDUSTRIAL PROCESS OF CATALYZING IN PRESENCE OF METALLIC PHOSPHATES RHONE-POULENC CHIMIE (FR) 1997-04-08 US claimed
CN-111902400-B Aromatic derivatives, process for their preparation and their medical use 保仕健生物科技(上海)有限公司 2024-08-30 CN disclosed
US-11976058-B2 Aromatic derivatives, preparation methods, and medical uses thereof BIOARDIS LLC (US) 2024-05-07 US disclosed
CN-112679328-B Industrial production method of 3-trifluoromethyl-2-cyclohexene-1-one 南京药石科技股份有限公司 2023-09-15 CN disclosed
US-20220169634-A1 AROMATIC DERIVATIVES, PREPARATION METHODS, AND MEDICAL USES THEREOF BIOARDIS LLC 2022-06-02 US disclosed
EP-3935048-A1 AROMATIC DERIVATIVES, PREPARATION METHODS, AND MEDICAL USES THEREOF Bioardis LLC (US) 2022-01-12 EP disclosed
EP-3050134-B9 PHOTOACTIVE ORGANIC MATERIAL FOR OPTOELECTRONIC COMPONENTS HELIATEK GMBH (DE) 2021-10-27 EP disclosed
EP-3050134-B1 PHOTOACTIVE ORGANIC MATERIAL FOR OPTOELECTRONIC COMPONENTS HELIATEK GMBH (DE) 2021-05-05 EP disclosed
CN-112679328-A Industrial production method of 3-trifluoromethyl-2-cyclohexene-1-ketone 南京药石科技股份有限公司 2021-04-20 CN disclosed
CN-111902400-A Aromatic derivatives, process for their preparation and their medical use 保仕健生物科技(上海)有限公司 2020-11-06 CN disclosed
US-20020161041-A1 Resorcinol derivatives PFIZER INC. 2002-10-31 US disclosed
US-6340775-B1 FORMING ALCOHOLS BY REDUCTION OF CARBONYL COMPOUNDS IN THE PRESENCE OF CATALYSTS RHODIA CHIMIE (FR) 2002-01-22 US disclosed
EP-1165495-A1 RESORCINOL DERIVATIVES PFIZER INC. (US) 2002-01-02 EP disclosed
WO-2000056702-A1 RESORCINOL DERIVATIVES PFIZER INC. (US) 2000-09-28 WO disclosed
EP-0956278-A1 METHOD FOR REDUCING A CARBONYL-CONTAINING COMPOUND RHODIA CHIMIE (FR) 1999-11-17 EP disclosed
WO-1998030517-A1 METHOD FOR REDUCING A CARBONYL-CONTAINING COMPOUND RHODIA CHIMIE (FR) 1998-07-16 WO disclosed
EP-0654460-B1 Process for the C-alkylation of a ketonic compound RHONE POULENC CHIMIE (FR) 1997-06-18 EP disclosed
US-5618982-A SIMPLE INDUSTRIAL PROCESS OF CATALYZING IN PRESENCE OF METALLIC PHOSPHATES RHONE-POULENC CHIMIE (FR) 1997-04-08 US disclosed
CN-1108659-A Trifluoroisopropenyl zinc reagent and its derivate application SHANGHAI INST ORGANIC CHEM (CN) 1995-09-20 CN disclosed
EP-0654460-A1 Process for the C-alkylation of a ketonic compound RHONE-POULENC CHIMIE (FR) 1995-05-24 EP disclosed