Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.51 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | DEGS1 | O15121 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4811455 | 0.87 | TRPV1 (0.65) | TRPV1TRPV4LMNA | |
| SCHEMBL4811896 | 0.86 | TRPV1 (0.67) | TRPV1CA12CA1CA9DEGS1 | |
| SCHEMBL4815470 | 0.84 | TRPV4 (0.56) | TRPV1TRPV4DEGS1SMN1; SMN2MEN1 | |
| SCHEMBL4806062 | 0.80 | TRPV1 (0.59) | TRPV1TRPV4 | |
| SCHEMBL4808062 | 0.79 | TRPV1 (0.69) | TRPV1TRPV4 | |
| SCHEMBL14083552 | 0.78 | TRPV1 (0.57) | TRPV1DEGS1MEN1KMT2ANPC1 | |
| SCHEMBL4591053 | 0.76 | TRPV1 (0.78) | TRPV1DEGS1 | |
| SCHEMBL4813597 | 0.75 | TRPV1 (0.65) | TRPV1 | |
| SCHEMBL4809369 | 0.75 | TRPV1 (0.71) | TRPV1TRPV4 | |
| SCHEMBL4816141 | 0.74 | TRPV4 (0.66) | TRPV1TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7338950-B2 | Amide compounds as ion channel ligands and uses thereof | RENOVIS, INC. (US) | 2008-03-04 | — | — | US | disclosed |