Chloroform

Chloroform

SCHEMBL48119

CO.ClC(Cl)Cl.ClC(Cl)Cl

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.57
TSHR P16473 2/20 0.44
ALDH1A1 P00352 2/20 0.44
TDP1 Q9NUW8 1/20 0.33
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloroform SCHEMBL2568782 1.00 LMNA (0.57) LMNATSHRALDH1A1TDP1HSD17B10
Chloroform SCHEMBL9568279 1.00 LMNA (0.57) LMNATSHRALDH1A1TDP1HSD17B10
Chloroform SCHEMBL5747359 1.00 LMNA (0.57) LMNATSHRALDH1A1TDP1HSD17B10
Chloroform SCHEMBL3207413 1.00 LMNA (0.57) LMNATSHRALDH1A1TDP1HSD17B10
Chloroform SCHEMBL888275 1.00 LMNA (0.57) LMNATSHRALDH1A1TDP1HSD17B10
Chloroform SCHEMBL9037829 1.00 LMNA (0.57) LMNATSHRALDH1A1TDP1HSD17B10
Chloroform SCHEMBL9526391 1.00 LMNA (0.57) LMNATSHRALDH1A1TDP1HSD17B10
Chloroform SCHEMBL9525441 1.00 LMNA (0.57) LMNATSHRALDH1A1TDP1HSD17B10
Chloroform SCHEMBL2571706 1.00 LMNA (0.57) LMNATSHRALDH1A1TDP1HSD17B10
Chloroform SCHEMBL9528226 1.00 LMNA (0.57) LMNATSHRALDH1A1TDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106631709-A Hydroxytyrosol extraction and nitration method 中国林业科学研究院林产化学工业研究所 2017-05-10 CN claimed
CN-102372721-A Preparation method for magnolin SUZHOU BAOZETANG MEDICAL TECH 2012-03-14 CN claimed
EP-4349331-A1 NOVEL AMP-ACTIVATED PROTEIN KINASE ACTIVATOR Kyoto Pharmaceutical University (JP) 2024-04-10 EP disclosed
US-11633493-B2 Antibody-drug conjugate DAIICHI SANKYO COMPANY, LIMITED (JP) 2023-04-25 US disclosed
US-11584800-B2 Method of treating cancer comprising administration of anti-HER2 antibody-drug conjugate DAIICHI SANKYO COMPANY, LIMITED (JP) 2023-02-21 US disclosed
WO-2022265069-A1 ENZYME-STABILIZING AGENT FOR DETERGENTS 花王株式会社 2022-12-22 WO disclosed
WO-2022255499-A1 NOVEL AMP-ACTIVATED PROTEIN KINASE ACTIVATOR 学校法人京都薬科大学 2022-12-08 WO disclosed
US-20220125943-A1 ANTIBODY-PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2022-04-28 US disclosed
US-11261261-B2 2022-03-01 US disclosed
WO-2021215522-A1 LINDERAPYRONE, AND ANALOGUE THEREOF 学校法人京都薬科大学 (JP) 2021-10-28 WO disclosed
US-10973924-B2 Antibody-drug conjugate DAIICHI SANKYO COMPANY, LIMITED (JP) 2021-04-13 US disclosed
EP-0376114-A2 9-Dihydro-9-0-alkyldesmycosin derivatives ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1990-07-04 EP disclosed
EP-0374095-A2 Piperidine derivatives CIBA-GEIGY AG (CH) 1990-06-20 EP disclosed
EP-0275312-A1 THIAZOLE DERIVATIVES OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1988-07-27 EP disclosed
US-4631149-A VIRICIDE, BACTERICIDE, ANTIBIOTIC, AND ANTITUMOR AGENT UNIVERSITY OF ILLINOIS (US) 1986-12-23 US disclosed
EP-0133000-A2 Antibiotics THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1985-02-13 EP disclosed
US-4331593-A TRIPEPTIDE SMITHWICK JR EDWARD L 1982-05-25 US disclosed
EP-0050407-A1 3,5-Disubstituted-1,2,4-triazole compounds, processes for their preparation and pharmaceutical compositions containing them GLAXO GROUP LIMITED (GB) 1982-04-28 EP disclosed
EP-0001684-B1 TETRAPEPTIDES, METHODS FOR THEIR PREPARATION AND THEIR USE IN ANALGESIC COMPOSITIONS ELI LILLY AND COMPANY (US) 1981-09-02 EP disclosed
US-4264491-A OLIGOPEPTIDE ELI LILLY AND COMPANY (US) 1981-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11633493-B2 Antibody-drug conjugate LANCL2, LANCL1, LCLAT1 LMNA 150/4885TSHR 1899/4885ALDH1A1 439/4885
US-10973924-B2 Antibody-drug conjugate LANCL2, LANCL1, LCLAT1 LMNA 97/4885TSHR 2226/4885ALDH1A1 569/4885
US-11261261-B2 ERBB2, EGFR, H1-2 LMNA 105/4885TSHR 1105/4885ALDH1A1 1166/4885
US-11584800-B2 Method of treating cancer comprising administration of anti-HER2 antibody-drug conjugate ERBB2, EGFR, H1-2 LMNA 160/4885TSHR 786/4885ALDH1A1 1073/4885
US-20220125943-A1 ANTIBODY-PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE PDCD6, EPCAM, CNTN1 LMNA 2692/4885TSHR 2286/4885ALDH1A1 2870/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.