Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL2568782 | 1.00 | LMNA (0.57) | LMNATSHRALDH1A1TDP1HSD17B10 | |
| Chloroform SCHEMBL9568279 | 1.00 | LMNA (0.57) | LMNATSHRALDH1A1TDP1HSD17B10 | |
| Chloroform SCHEMBL5747359 | 1.00 | LMNA (0.57) | LMNATSHRALDH1A1TDP1HSD17B10 | |
| Chloroform SCHEMBL3207413 | 1.00 | LMNA (0.57) | LMNATSHRALDH1A1TDP1HSD17B10 | |
| Chloroform SCHEMBL888275 | 1.00 | LMNA (0.57) | LMNATSHRALDH1A1TDP1HSD17B10 | |
| Chloroform SCHEMBL48119 | 1.00 | LMNA (0.57) | LMNATSHRALDH1A1TDP1HSD17B10 | |
| Chloroform SCHEMBL9526391 | 1.00 | LMNA (0.57) | LMNATSHRALDH1A1TDP1HSD17B10 | |
| Chloroform SCHEMBL9525441 | 1.00 | LMNA (0.57) | LMNATSHRALDH1A1TDP1HSD17B10 | |
| Chloroform SCHEMBL2571706 | 1.00 | LMNA (0.57) | LMNATSHRALDH1A1TDP1HSD17B10 | |
| Chloroform SCHEMBL9528226 | 1.00 | LMNA (0.57) | LMNATSHRALDH1A1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393574-B1 | Hexitol derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-01-31 | — | — | EP | disclosed |
| EP-0393574-A2 | Hexitol derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-10-24 | — | — | EP | disclosed |