SCHEMBL481235

SCHEMBL481235

C=C(C)C(=O)OCCCCC12CCCCC1C(=O)NC2=O

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
NAAA Q02083 10/20 0.34
ASAH1 Q13510 1/20 0.32
THRB P10828 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL481526 0.97 TSHR (0.37) TSHRPOLBAPEX1HTTTDP1
SCHEMBL5447282 0.68 TSHR (0.41) TSHRPOLBAPEX1HTTTDP1
SCHEMBL422110 0.67 TSHR (0.56) TSHRPOLBAPEX1HTTTDP1
SCHEMBL5144090 0.66 TSHR (0.79) TSHRPOLBAPEX1HTTTDP1
SCHEMBL25426 0.66 TSHR (0.79) TSHRPOLBAPEX1HTTTDP1
SCHEMBL21110931 0.65 TSHR (0.46) TSHRPOLBAPEX1HTTTDP1
SCHEMBL16990466 0.65 ALDH1A1 (0.33) POLBTDP1ALDH1A1
SCHEMBL27501921 0.65 TSHR (0.49) TSHRPOLBAPEX1HTTTDP1
SCHEMBL28271140 0.65 EPHX1 (0.55) TSHRNAAAASAH1
SCHEMBL23494112 0.64 TSHR (0.51) TSHRNAAAASAH1THRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8859633-B2 Adherent composition and method of temporarily fixing member therewith DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2014-10-14 US disclosed
US-8187411-B2 Adherent composition and method of temporarily fixing member therewith DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2012-05-29 US disclosed
EP-1860128-B1 ADHERENT COMPOSITION AND METHOD OF TEMPORARILY FIXING MEMBER THEREWITH DENKI KAGAKU KOGYO KK (JP) 2012-02-01 EP disclosed
US-20110265934-A1 ADHERENT COMPOSITION AND METHOD OF TEMPORARILY FIXING MEMBER THEREWITH DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2011-11-03 US disclosed
US-20080149270-A1 Curable composition of polymerized conjugated diolefin having uretane (meth)acrylate end groups, di(meth)acrylate, monoacrylate and photopolymerization initiator; water-soluble adhesives easily swellable/removeable from optical lenses, prisms, silicon wafers, semiconductor parts; packaging; solvent-free DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2008-06-26 US disclosed
EP-1860128-A1 ADHERENT COMPOSITION AND METHOD OF TEMPORARILY FIXING MEMBER THEREWITH DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2007-11-28 EP disclosed