Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 2/20 | 0.55 |
| ▸ | SLC6A3 known ✓ | Q01959 | 2/20 | 0.55 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.55 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.55 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.55 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | TACR2 | P21452 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SHBG | P04278 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4813332 | 1.00 | ESR1 (0.55) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| Bromide SCHEMBL11492916 | 0.96 | ESR1 (0.55) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| Hydrochloric Acid SCHEMBL11193237 | 0.85 | HTR2A (0.59) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| Hydrochloric Acid SCHEMBL11428130 | 0.85 | HTR2A (0.59) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| Hydrochloric Acid SCHEMBL10716225 | 0.85 | HTR2A (0.59) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| Hydrochloric Acid SCHEMBL9625672 | 0.85 | HTR2A (0.59) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| Hydrochloric Acid SCHEMBL6511256 | 0.83 | KMT2A (0.64) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| Hydrochloric Acid SCHEMBL11429242 | 0.83 | KMT2A (0.64) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| Hydrochloric Acid SCHEMBL6512691 | 0.83 | KMT2A (0.64) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| Hydrochloric Acid SCHEMBL6521656 | 0.83 | KMT2A (0.64) | ESR1ADRA2AADORA3TACR2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7404915-B2 | Electromagnetic wave shielding material, method of manufacturing the same and electromagnetic wave shielding material for plasma display panel | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2008-07-29 | — | — | US | disclosed |
| US-20070138441-A1 | Electromagnetic wave shielding material, method of manufacturing the same and electromagnetic wave shielding material for plasma display panel | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2007-06-21 | — | — | US | disclosed |
| US-20070015094-A1 | ELECTROMAGNETIC WAVE SHIELDING MATERIAL, METHOD FOR MANUFACTURING THE SAME AND ELECTROMAGNETIC WAVE SHIELDING MATERIAL FOR PLASMA DISPLAY PANEL | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2007-01-18 | — | — | US | disclosed |