Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | TET3 | O43151 | 2/20 | 0.62 |
| ▸ | FBXL19 | Q6PCT2 | 2/20 | 0.62 |
| ▸ | CXXC5 | Q7LFL8 | 2/20 | 0.62 |
| ▸ | TET1 | Q8NFU7 | 2/20 | 0.62 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.62 |
| ▸ | CXXC4 | Q9H2H0 | 2/20 | 0.62 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.62 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232365 | 0.95 | KMT2A (0.73) | KMT2AMEN1TSHRTET3FBXL19 | |
| SCHEMBL4342214 | 0.92 | KMT2A (0.68) | KMT2AMEN1TSHRTET3FBXL19 | |
| SCHEMBL4812962 | 0.86 | KMT2A (0.57) | KMT2AMEN1TSHRTET3FBXL19 | |
| SCHEMBL5510283 | 0.86 | KMT2A (0.57) | KMT2AMEN1TSHRTET3FBXL19 | |
| SCHEMBL21874064 | 0.83 | KMT2A (0.68) | KMT2AMEN1TSHRTET3FBXL19 | |
| SCHEMBL28507069 | 0.82 | KMT2A (0.57) | KMT2AMEN1TSHRTET3FBXL19 | |
| SCHEMBL21874269 | 0.82 | KMT2A (0.63) | KMT2AMEN1TSHRTET3FBXL19 | |
| SCHEMBL503877 | 0.82 | KMT2A (0.63) | KMT2AMEN1TSHRTET3FBXL19 | |
| SCHEMBL5508063 | 0.81 | KMT2A (0.55) | KMT2AMEN1TSHRTET3FBXL19 | |
| SCHEMBL21874210 | 0.81 | MEN1 (0.62) | KMT2AMEN1TSHRAKR1C1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112210156-A | Ceramic halogen-free flame-retardant polymer composite material and application thereof | 宁夏师范学院 | 2021-01-12 | — | — | CN | disclosed |
| US-7465719-B2 | Carbamic acid compounds comprising an ester or ketone linkage as HDAC inhibitors | TOPOTARGET UK LIMITED (GB) | 2008-12-16 | — | — | US | disclosed |
| US-7465719-B2 | Carbamic acid compounds comprising an ester or ketone linkage as HDAC inhibitors | TOPOTARGET UK LIMITED (GB) | 2008-12-16 | — | — | US | disclosed |
| US-7465719-B2 | Carbamic acid compounds comprising an ester or ketone linkage as HDAC inhibitors | TOPOTARGET UK LIMITED (GB) | 2008-12-16 | — | — | US | disclosed |
| US-20060058282-A1 | Carbamic acid compounds comprising an ester or ketone linkage as hdac inhibitors | TOPOTARGET UK LIMITED (GB) | 2006-03-16 | — | — | US | disclosed |
| EP-1583736-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN ESTER OR KETONE LINKAGE AS HDAC INHIBITORS | TopoTarget UK Limited (GB) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004065354-A1 | CARBAMIC ACID COMPOUNDS COMPRISING AN ESTER OR KETONE LINKAGE AS HDAC INHIBITORS | TOPOTARGET UK LIMITED (GB) | 2004-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058282-A1 | Carbamic acid compounds comprising an ester or ketone linkage as hdac inhibitors | HDAC1, HDAC7, HDAC11 | KMT2A 86/4885MEN1 3250/4885TSHR 4107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.