Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | TET3 | O43151 | 1/20 | 0.49 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.49 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.49 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.49 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.49 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.49 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5510283 | 0.95 | KMT2A (0.57) | KMT2AMEN1TSHRPARP10TET3 | |
| SCHEMBL11232365 | 0.86 | KMT2A (0.73) | KMT2AMEN1TSHRPARP10TET3 | |
| SCHEMBL10002472 | 0.82 | LMNA (0.60) | KMT2AMEN1TSHRPARP10TET3 | |
| SCHEMBL4812653 | 0.81 | KMT2A (0.76) | KMT2AMEN1TSHRPARP10TET3 | |
| SCHEMBL7706230 | 0.81 | LMNA (0.56) | KMT2AMEN1TSHRPARP10LMNA | |
| SCHEMBL4812962 | 0.80 | KMT2A (0.57) | KMT2AMEN1TSHRPARP10TET3 | |
| SCHEMBL5205623 | 0.79 | LMNA (0.65) | KMT2AMEN1TSHRPARP10TET3 | |
| SCHEMBL4342214 | 0.79 | KMT2A (0.68) | KMT2AMEN1TSHRPARP10TET3 | |
| SCHEMBL2112323 | 0.78 | LMNA (0.68) | KMT2AMEN1TSHRPARP10LMNA | |
| SCHEMBL14161396 | 0.76 | LMNA (0.53) | KMT2AMEN1LMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814866-A2 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2007-08-08 | — | — | EP | claimed |
| WO-2006058012-A2 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS | WYETH (US) | 2006-06-01 | — | — | WO | claimed |