SCHEMBL4812796

SCHEMBL4812796

Brc1ccccc1C(Br)(c1ccccc1)C(Br)(Br)C(Br)(Br)Br

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA5A P35218 1/20 0.36
CA9 Q16790 1/20 0.36
ALDH1A1 P00352 3/20 0.32
MAPK1 P28482 1/20 0.32
KCNN4 O15554 2/20 0.31
TSHR P16473 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4813388 0.94 CA1 (0.35) CA1CA2CA5ACA9ALDH1A1
SCHEMBL652272 0.87 CA1 (0.38) CA1CA2CA5ACA9ALDH1A1
SCHEMBL4813318 0.86 CA1 (0.30) CA1CA2CA5ACA9
SCHEMBL2520732 0.81
SCHEMBL4812311 0.79 KCNN4 (0.41) ALDH1A1MAPK1KCNN4TSHR
SCHEMBL4812616 0.79
SCHEMBL1226128 0.77
SCHEMBL4944865 0.75 CA1 (0.30) CA1CA2CA5ACA9
SCHEMBL653490 0.73 CA1 (0.32) CA1CA2CA5ACA9ALDH1A1
SCHEMBL21763332 0.73 CA1 (0.41) CA1CA2CA5ACA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7405254-B2 Brominated anionic styrenic polymer, and decabromodiphenylpropane or decabromodiphenylethane ALBEMARLE CORPORATION (US) 2008-07-29 US disclosed
EP-1711555-B1 FLAME RETARDANT COMPOSITIONS AND THEIR USE ALBEMARLE CORP (US) 2008-07-09 EP disclosed
US-20070117904-A1 Flame Retardant Compositions and Their Use ALBEMARLE CORPORATION (US) 2007-05-24 US disclosed
US-7202296-B2 Flame retardant compositions and their use ALBEMARLE CORPORATION (US) 2007-04-10 US disclosed
EP-1711555-A1 FLAME RETARDANT COMPOSITIONS AND THEIR USE ALBEMARLE CORPORATION (US) 2006-10-18 EP disclosed
WO-2005063869-A1 FLAME RETARDANT COMPOSITIONS AND THEIR USE ALBEMARLE CORPORATION (US) 2005-07-14 WO disclosed
US-20050137311-A1 Flame retardant compositions and their use ALBEMARLE CORPORATION 2005-06-23 US disclosed