SCHEMBL4944865

SCHEMBL4944865

Brc1cccc(C(Br)(c2ccccc2)C(Br)(Br)C(Br)(Br)C(Br)(Br)C(Br)(Br)C(Br)(Br)C(Br)(Br)C(Br)(Br)C(Br)(Br)C(Br)(c2ccccc2)c2ccccc2)c1Br

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA5A P35218 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2520732 0.91
SCHEMBL4813318 0.89 CA1 (0.30) CA1CA2CA5ACA9
SCHEMBL4951380 0.85
SCHEMBL653490 0.85 CA1 (0.32) CA1CA2CA5ACA9
SCHEMBL4813388 0.77 CA1 (0.35) CA1CA2CA5ACA9
SCHEMBL29197463 0.76 ALDH1A1 (0.33) CA1CA2CA5ACA9
SCHEMBL9016955 0.76 ALDH1A1 (0.33) CA1CA2CA5ACA9
SCHEMBL4949544 0.76 ALDH1A1 (0.32) CA1CA2CA5ACA9
SCHEMBL4812796 0.75 CA1 (0.36) CA1CA2CA5ACA9
SCHEMBL8854169 0.75 KCNN4 (0.41) CA1CA2CA5ACA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7378449-B2 Poly(bromoaryl)alkane additives and methods for their preparation and use ALBEMARLE CORPORATION (US) 2008-05-27 US disclosed
US-20070093582-A1 POLY(BROMOARYL)ALKANE ADDITIVES AND METHODS FOR THEIR PREPARATION AND USE ALBEMARLE CORPORATION (US) 2007-04-26 US disclosed
US-7129385-B2 Poly(bromoaryl)alkane additives and methods for their preparation and use ALBEMARLE CORPORATION (US) 2006-10-31 US disclosed
US-20040195087-A1 Poly(bromoaryl)alkane additives and methods for their preparation and use ALBEMARLE CORPORATION 2004-10-07 US disclosed
US-6743825-B1 Poly(bromoaryl)alkane additives and methods for their preparation and use ALBEMARLE CORPORATION 2004-06-01 US disclosed