SCHEMBL653490

SCHEMBL653490

Brc1cccc(C(Br)(c2ccccc2)C(Br)(Br)Br)c1Br

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA5A P35218 1/20 0.32
CA9 Q16790 1/20 0.32
ALDH1A1 P00352 2/20 0.31
MAPK1 P28482 1/20 0.31
KCNN4 O15554 2/20 0.31
TSHR P16473 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4813318 0.89 CA1 (0.30) CA1CA2CA5ACA9
SCHEMBL2520732 0.87
SCHEMBL652272 0.85 CA1 (0.38) CA1CA2CA5ACA9ALDH1A1
SCHEMBL4944865 0.85 CA1 (0.30) CA1CA2CA5ACA9
SCHEMBL653727 0.84 TSHR (0.30) ALDH1A1KCNN4TSHR
SCHEMBL4809742 0.79
SCHEMBL9016955 0.79 ALDH1A1 (0.33) CA1CA2CA5ACA9ALDH1A1
SCHEMBL29197463 0.79 ALDH1A1 (0.33) CA1CA2CA5ACA9ALDH1A1
SCHEMBL8854169 0.78 KCNN4 (0.41) CA1CA2CA5ACA9ALDH1A1
SCHEMBL653858 0.74 TDP1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117776859-B Preparation, separation and purification method of decabromodiphenyl ethane debromination product 山东科技大学 2024-05-17 CN claimed
CN-117776859-A Preparation, separation and purification method of decabromodiphenyl ethane debromination product 山东科技大学 2024-03-29 CN claimed
CN-115850958-A Flame-retardant polyamide elastomer material and preparation method and application thereof 沧州旭阳化工有限公司 2023-03-28 CN claimed
US-8354464-B2 Mixtures of brominated diphenylethanes, method of preparing the same and resin composition using the same CHEIL INDUSTRIES INC. (KR) 2013-01-15 US claimed
US-8334332-B2 Flame-retardant thermoplastic resin composition with excellent color tone CHEIL INDUSTRIES INC. (KR) 2012-12-18 US claimed
US-8329804-B2 Flame retardant thermoplastic resin composition CHEIL INDUSTRIES INC. (KR) 2012-12-11 US claimed
US-8193272-B2 Flame-retardant high impact vinyl aromatic resin composition having good fluidity CHEIL INDUSTRIES INC. (KR) 2012-06-05 US claimed
US-8119720-B2 Thermoplastic resin composition having improved flowability CHEIL INDUSTRIES INC. (KR) 2012-02-21 US claimed
US-7977421-B2 Brominated diphenyl ethane mixtures and resin compositions including the same CHEIL INDUSTRIES INC. (KR) 2011-07-12 US claimed
US-20110160343-A1 Flame-Retardant Thermoplastic Resin Composition with Excellent Color Tone CHEIL INDUSTRIES INC. (KR) 2011-06-30 US claimed
US-20050009992-A1 Carbon-carbon initiators for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-01-13 US claimed
US-6117371-A FLAME RETARDANT OF HEXABROMODIPHENYLALKANE, HEPTABROMODIPHENYLALKANE, AND OCTABROMODIPHENYLALKANE WHICH HAS A BROAD MELTING POINT RANGE; FLAMMABLE POLYMER AND FLAME RETARDANT GREAT LAKES CHEMICAL CORPORATION (US) 2000-09-12 US claimed
EP-0784648-A4 CONTINUOUS BROMINATION PROCESS AND PRODUCTS THEREOF GREAT LAKES CHEMICAL CORP (US) 2000-02-02 EP claimed
EP-0784648-A1 CONTINUOUS BROMINATION PROCESS AND PRODUCTS THEREOF GREAT LAKES CHEMICAL CORPORATION (US) 1997-07-23 EP claimed
WO-1996011227-A1 CONTINUOUS BROMINATION PROCESS AND PRODUCTS THEREOF GREAT LAKES CHEMICAL CORPORATION (US) 1996-04-18 WO claimed
EP-0502333-A1 Bromination process ALBEMARLE CORPORATION (US) 1992-09-09 EP claimed
EP-0490378-A1 Bromination process ALBEMARLE CORPORATION (US) 1992-06-17 EP claimed
US-5055235-A Heating non-condensed ring polyaromatics in the presence of bromine and a halogenation catalyst ETHYL CORPORATION (US) 1991-10-08 US claimed
EP-0445595-A2 Bromination process ALBEMARLE CORPORATION (US) 1991-09-11 EP claimed
US-5039729-A Consisting of hexabromodiphenyl ethane, heptabromodiphenyl ethane and octabromodiphenyl ethane; flame retarders ETHYL CORPORATION (US) 1991-08-13 US claimed