Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 11/20 | 0.52 |
| ▸ | CES2 | O00748 | 6/20 | 0.52 |
| ▸ | FAAH | O00519 | 11/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3778978 | 0.89 | FAAH (0.59) | CES1CES2FAAHMEN1CYP1A2 | |
| SCHEMBL3777162 | 0.89 | FAAH (0.59) | CES1CES2FAAHMEN1CYP1A2 | |
| SCHEMBL9435633 | 0.89 | FAAH (0.59) | CES1CES2FAAHMEN1CYP1A2 | |
| SCHEMBL3787603 | 0.89 | FAAH (0.59) | CES1CES2FAAHMEN1CYP1A2 | |
| SCHEMBL3777756 | 0.89 | FAAH (0.59) | CES1CES2FAAHMEN1CYP1A2 | |
| SCHEMBL8013027 | 0.86 | CES1 (0.52) | CES1CES2FAAHMEN1CYP1A2 | |
| SCHEMBL8015133 | 0.86 | CES1 (0.52) | CES1CES2FAAHMEN1CYP1A2 | |
| SCHEMBL3437239 | 0.86 | CES1 (0.52) | CES1CES2FAAHMEN1CYP1A2 | |
| SCHEMBL8015947 | 0.86 | CES1 (0.52) | CES1CES2FAAHMEN1CYP1A2 | |
| SCHEMBL4803939 | 0.81 | FAAH (0.52) | CES1CES2FAAHMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7329795-B2 | Model animals non-responsive to mycobacterial-origin lipoprotein/lipopeptide | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-02-12 | — | — | US | disclosed |
| US-20060059579-A1 | Model animals non-responsive to mycobacteria-origin lipoprotein/lipopeptide | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2006-03-16 | — | — | US | disclosed |