Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | MELK | Q14680 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749038 | 0.91 | PARP1 (0.43) | OPRD1KDM1AMAOAMAOB | |
| SCHEMBL4749047 | 0.91 | PARP1 (0.43) | OPRD1KDM1AMAOAMAOB | |
| SCHEMBL4019710 | 0.90 | RORC (0.43) | RORCMEN1KMT2AGRIN2BKDM1A | |
| SCHEMBL4024572 | 0.90 | RORC (0.43) | RORCMEN1KMT2AGRIN2BKDM1A | |
| SCHEMBL4019712 | 0.90 | RORC (0.43) | RORCMEN1KMT2AGRIN2BKDM1A | |
| SCHEMBL4024492 | 0.90 | DRD2 (0.43) | RORCMEN1KMT2AGRIN2BDRD3 | |
| SCHEMBL4020117 | 0.90 | GRIN2B (0.40) | GRIN2BDRD3DRD2 | |
| SCHEMBL4020120 | 0.90 | GRIN2B (0.40) | GRIN2BDRD3DRD2 | |
| SCHEMBL4024495 | 0.90 | DRD2 (0.43) | RORCMEN1KMT2AGRIN2BDRD3 | |
| SCHEMBL4751419 | 0.89 | MEN1 (0.40) | OPRD1MEN1KMT2AGRIN2BMELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |