Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.35 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | IFNAR1 | P17181 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4904964 | 0.75 | HTR6 (0.46) | LMNAALDH1A1POLBNPY1RMAPK1 | |
| Formic Acid SCHEMBL4813546 | 0.74 | CHAT (0.42) | LMNAPOLB | |
| SCHEMBL4824600 | 0.69 | SLC6A4 (0.52) | LMNAALDH1A1IFNAR1NPY1RMAPK1 | |
| SCHEMBL4824586 | 0.69 | SLC6A4 (0.52) | LMNAALDH1A1IFNAR1NPY1RMAPK1 | |
| SCHEMBL4822755 | 0.62 | SLC6A4 (0.48) | LMNAALDH1A1IFNAR1NPY1RMAPK1 | |
| SCHEMBL14027232 | 0.62 | SLC6A2 (0.40) | HPGDLMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL3077714 | 0.60 | MEN1 (0.61) | HPGDKMT2AALDH1A1MEN1GAA | |
| SCHEMBL4824477 | 0.60 | OPRL1 (0.41) | LMNAALDH1A1IFNAR1NPY1RMAPK1 | |
| SCHEMBL6057233 | 0.60 | POLB (0.57) | HPGDLMNAALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL5658529 | 0.60 | TDP1 (0.69) | HPGDLMNAKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375125-B2 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |