Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745024 | 0.78 | TSHR (0.39) | ALDH1A1GAATSHRNISCHKDM4E | |
| Formic Acid SCHEMBL4814029 | 0.77 | POLB (0.36) | EGFRERBB2ALDH1A1CYP2C9GAA | |
| SCHEMBL4070724 | 0.67 | NISCH (0.51) | GAATSHRNISCHL3MBTL1 | |
| Bromide SCHEMBL4909528 | 0.66 | NISCH (0.50) | GAATSHRNISCHL3MBTL1 | |
| SCHEMBL10997977 | 0.63 | L3MBTL1 (0.68) | GAATSHRNISCHLMNAL3MBTL1 | |
| SCHEMBL4823615 | 0.62 | NISCH (0.57) | GAATSHRNISCHL3MBTL1 | |
| SCHEMBL4825348 | 0.61 | NISCH (0.52) | GAATSHRNISCH | |
| SCHEMBL4071617 | 0.59 | NISCH (0.61) | ALDH1A1TSHRNISCHKDM4ELMNA | |
| SCHEMBL4013195 | 0.59 | PPARG (0.43) | CYP2C9GAATSHRNISCHPPARG | |
| SCHEMBL4159436 | 0.59 | NISCH (0.49) | GAATSHRNISCHL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375125-B2 | Melanocortin-4 receptor binding compounds and methods of use thereof | ORE PHARMACEUTICALS, INC. (US) | 2008-05-20 | — | — | US | disclosed |